Juvenile Idiopathic Arthritis Flashcards
What are other names for juvenile idiopathic arthritis (JIA)?
juvenile rheumatoid arthritis (JRA)
juvenile chronic arthritis (JCA)
Define juvenile idiopathic arthritis
an inflammatory arthropathy with an onset prior to 16 years of age
(i.e., a 30 year old that comes into your office would have JIA, bc different manifestations than adult onset RA)
Lab results that are positive for RF are termed ____, while labs that are negative for RF are termed ____
seropositive
seronegative
Seropositive juvenile arthritis is called ____
Still disease
What are the 2 types of seronegative juvenile arthropathies?
Polyarticular
Pauciarticular
What are the relevant lab findings for seropositive arthritis?
- RF positive
- ANA positive
- HLA-D4 positive
Still disease is (monoarticular/polyarticular)
polyarticular
What sex is most affected by Still disease?
Female
> 50% of patients with seropositive arthritis will develop _____
severe disease
What are the 2 subcategories of seronegative polyarticular arthritis?
- without systemic symptoms (arthritis only)
- with systemic symptoms
Seronegative polyarticular arthritis involves how many joints?
> 5
Seronegative pauciarticular arthritis involves how many joints?
<4-5
What systemic symptoms may present with seronegative polyarticular arthritis?
- fever
- rash
- hepatosplenomegaly
- lymphadenopathy
- pleuritis
- anemia of chronic disease (fatigue)
- leukocytosis
What joints are most commonly affected by pauciarticular arthritis?
- knee
- ankle
- elbow
- hip
What are the 2 subcategories of seronegative pauciarticular arthritis? Which is more common?
female > male
What are the relevant lab findings for female seronegative pauciarticular arthritis?
- RF negative
- ANA positive
- HLA positive
What are the relevant lab findings for male seronegative pauciarticular arthritis?
- RF negative
- ANA negative
- HLA-B27 positive
What type of JIA is typically self-limiting?
seronegative pauciarticular arthritis
What is a potential long term concern for males with seronegative pauciarticular arthritis?
ankylosing spondylitis
Which type of JIA can have ocular inflammation of the iris and ciliary body?
seronegative pauciarticular arthritis
