Juvenile Idiopathic Arthritis Flashcards

1
Q

What are other names for juvenile idiopathic arthritis (JIA)?

A

juvenile rheumatoid arthritis (JRA)
juvenile chronic arthritis (JCA)

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2
Q

Define juvenile idiopathic arthritis

A

an inflammatory arthropathy with an onset prior to 16 years of age
(i.e., a 30 year old that comes into your office would have JIA, bc different manifestations than adult onset RA)

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3
Q

Lab results that are positive for RF are termed ____, while labs that are negative for RF are termed ____

A

seropositive
seronegative

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4
Q

Seropositive juvenile arthritis is called ____

A

Still disease

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5
Q

What are the 2 types of seronegative juvenile arthropathies?

A

Polyarticular
Pauciarticular

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6
Q

What are the relevant lab findings for seropositive arthritis?

A
  • RF positive
  • ANA positive
  • HLA-D4 positive
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7
Q

Still disease is (monoarticular/polyarticular)

A

polyarticular

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8
Q

What sex is most affected by Still disease?

A

Female

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9
Q

> 50% of patients with seropositive arthritis will develop _____

A

severe disease

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10
Q

What are the 2 subcategories of seronegative polyarticular arthritis?

A
  • without systemic symptoms (arthritis only)
  • with systemic symptoms
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11
Q

Seronegative polyarticular arthritis involves how many joints?

A

> 5

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12
Q

Seronegative pauciarticular arthritis involves how many joints?

A

<4-5

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13
Q

What systemic symptoms may present with seronegative polyarticular arthritis?

A
  • fever
  • rash
  • hepatosplenomegaly
  • lymphadenopathy
  • pleuritis
  • anemia of chronic disease (fatigue)
  • leukocytosis
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14
Q

What joints are most commonly affected by pauciarticular arthritis?

A
  • knee
  • ankle
  • elbow
  • hip
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15
Q

What are the 2 subcategories of seronegative pauciarticular arthritis? Which is more common?

A

female > male

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16
Q

What are the relevant lab findings for female seronegative pauciarticular arthritis?

A
  • RF negative
  • ANA positive
  • HLA positive
17
Q

What are the relevant lab findings for male seronegative pauciarticular arthritis?

A
  • RF negative
  • ANA negative
  • HLA-B27 positive
18
Q

What type of JIA is typically self-limiting?

A

seronegative pauciarticular arthritis

19
Q

What is a potential long term concern for males with seronegative pauciarticular arthritis?

A

ankylosing spondylitis

20
Q

Which type of JIA can have ocular inflammation of the iris and ciliary body?

A

seronegative pauciarticular arthritis