Juvenile Idiopathic Arthritis Flashcards

1
Q

JIA is what type of disease

A

Autoimmune

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2
Q

Age of Onset of JIA

A

<16 years

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3
Q

Duration of Onset of JIA

A

> 6 Weeks

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4
Q

JIA Features

A

Joint Swell or 2 of following

  • Painful or Limited Joint Motion
  • Tender
  • Warmth
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5
Q

The most common type of JIA

A

Pauciarticular JIA

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6
Q

Pauchiarticular JIA affects how many joints

A

4 or less

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7
Q

When does Pauchiarticular JIA peak

A

2-4 years old

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8
Q

Girls to Boys Pauchiarticular Type 1 JIA Ratio

A

8:1

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9
Q

Pauchiarticular Type 1 JIA presentation

A
limp not pain
LL joints
Knee most common
\+ANA
irregular iris due to posterior synchiae
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10
Q

Pauchiarticular Type 2 JIA Features

A
15%
Age 8+
More common Girls
Limp
Lower Limb: Knee, Ankle
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11
Q

Pauchiarticular Type 2 JIA Those with HLA B27 and Back involvement will be categorised as

A

Juvenile Ankylosing Spondylitis

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12
Q

Pauchiarticular Type 3 JIA presentation

A

Assymetric LL and UL arthritis

Dactylitis

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13
Q

What is Polyarticular JIA

A

5 or More Joints

Second most common type of JIA

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14
Q

Presentation of Polyarticular JIA RF -VE

A
Low Grade Fever
Malaise
Hepatomegaly
Mild Anaemia
Growth Abnormality
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15
Q

Who does Polyarticular JIA RF +Ve affect?

A

Teens

Girls

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16
Q

Presentation of Polyarticular JIA RF +Ve

A
Low Grade Fever
Malaise
Weight Loss
Anaemia
Nodules
Erosions in X-ray
17
Q

Systemic Onset JIA is called

A

Still’s Disease

18
Q

Systemic Onset JIA Symptoms appear/disappear within

19
Q

Systemic Onset JIA fever rises to

A

39.5 for 2 weeks

returns to normal in morning

20
Q

Systemic Onset JIA rash

A

90%
evanescent salmon red eruption
on trunk and thighs
accompanies fever

21
Q

what is koebener phenomenon related to

A

scratching in Systemic Onset JIA

22
Q

Polyserositis related to which JIA

A

Systemic Onset JIA

23
Q

Arthritis onsets within how long of Systemic Onset JIA

A

3-12 months after onset of fever

24
Q

which part of spine can arthritis onset in Systemic onset JIA

A

cervical spine

25
where can arthritis affect in systemic onset JIA
``` Cervical Spine Wrist Ankles TMJ Knees Hips ```
26
Uveitis is present particularly with what JIA conditions
Oligo-articular | Extended Oligo
27
Uveitis significantly related to what ANA patients
Ana Positive
28
Most common non infective cause of uveitis
JIA
29
Complications of Uveitis in JIA
Posterior Synchiae Cataract Band Keratopathy
30
Uveitis in JIA treatment
``` Steroids Mydriatic and Cycloplegic Agents Methotrexate MMF Cicilosporin Anti TNF ```
31
2nd Line therapy for JIA
Methotrexate
32
In Methotrexate failure in JIA
Anti TNF
33
For refractory systemic arthritis | treatment in JIA
IL R Antagonist (Anakinra)
34
For refractory systemic disease treatment in JIA
IL 6 Antagonist (Toclizumab)
35
1st Line treatment for JIA
NSAIDS | Pain Killers