Crystal Deposition Diseases

Question 1

What are Crystal Deposition Diseases characterised by

Answer 1

deposition of mineralised material within joints and peri-articular tissue

Question 2

Monosodium Urate causes which crystal deposition disease

Answer 2

Gout

Question 3

Calcium pyrophosphate dihydrate (CPPD) causes

Answer 3

Pseudogout

Question 4

Basic calcium phosphate hydroxy-apatite (BCP) causes

Answer 4

calcific periarthritis/tendonitis

Question 5

Crystal deposition diseases causes

Answer 5

massive accumulations of uric acid

Question 6

Acute Flare of Gout Management

Answer 6

NSAIDS
Colchicine
Steroids: IA/IM/Oral

Question 7

How to Lower Uric Acid

Answer 7

1. Xanthine Oxidase inhibitor
2. Febuxostat
3. Uricosuric Agents
4. Canakinumab

Question 8

Name a Xanthine Oxidase inhibitor used to lower uric acid

Answer 8

Allopurinol

Question 9

Name three uricosuric agents

Answer 9

Sulphinpyrazone
Probenecid
Benzbromarone

Question 10

Rules for lowering uric acid levels

Answer 10

1. Wait until acute attack settled before reduce rate level
2. Prophylactic NSAIDS or low dose colchicine/steroids until rate level normal
3. Adjust allopurinol dose according to renal function