Ankylosing Spondylitis Flashcards

1
Q

What is Ankylosing Spondylitis

A

Chronic inflammatory rheumatic disorder with a predilection for axial skeleton and entheses

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2
Q

When is onset of Ankylosing spondylitis

A

2nd-3rd Decade of Life

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3
Q

Ankylosing spondylitis more common in

A

males

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4
Q

Which molecule associated with Ankylosing spondylitis

A

HLA B27

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5
Q

Test for Spinal Mobility in Ankylosing spondylitis

A

Modified Schober

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6
Q

What does Modified Schober test in Ankylosing spondylitis do

A

Mark between Pos Sup Iliac Spines

Measure Difference

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7
Q

Test for Spinal Mobility in Ankylosing spondylitis

A

Lateral Spinal Flexion

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8
Q

Test for Spinal Mobility in Ankylosing spondylitis

A

Occiput to Wall
Tragus to wall
Cervical Rotation

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9
Q

Ankylosing spondylitis Clinical Features

A

Inflammatory Back Pain
Limitation of movements in antero-posterior as well as lateral planes at lumbar spine
Limitation of chest expansion
Bilateral sacroiliitis on X-rays

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10
Q

What would x ray show in Ankylosing Spondylitis

A

Bilateral Sarcoilitis

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11
Q

Grading of Radiographic Sacroilitis 1

A

Suspicious Changes

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12
Q

Grading of Radiographic Sacroilitis 2

A

Minimal Abnormality without Alteration in joint width

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13
Q

Grading of Radiographic Sacroilitis 3

A

Unequivocal abnormality: mod or advanced sacroilitis with erosions, sclerosis, widening, narrow or partial ankylosis

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14
Q

Grading of Radiographic Sacroilitis 4

A

Severe abnormality: total ankylosis

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15
Q

Syndesmorphytes are in what stage of Axial Spondyloarthritus

A

Late

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16
Q

Axial Spondyloarthritis should be suspected in what demographic of patients

A

> 3 months back pain

<45 at age of onset

17
Q

Criteria for Classification for Axial Spondyloarthritis

A

Sacroilitis on Imaging plus >1 SPA Feature or

HLA B27 plus >2 other Spa Features

18
Q

Spa Features in Axial Spondyloarthritis

A
Inflammatory Back Pain
Arthritis
Enthesitis in Heel
Uveitis
Dactylitis
Psoriasis
Crohns/Colitis
Respond to NSAIDS
Family History
HLA B27
Elevated CRP
19
Q

Management of AS in RA

A
Physio
NSAIDS
DMARDS: Sulfasalzine 
Anti TNF
Anti IL-17
Treat Osteoporosis
20
Q

which dmard to use in Axial Spondylitis

A

Sulfasalazine