Joints Flashcards

1
Q

Phases of osteoarthritis (3):

A
  1. Chondrocyte injury
  2. Chondrocytes proliferate
  3. Chondrocyte drop out with loss of cartilage
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2
Q

Bone eburnation:

A

Seen in osteoarthritis: bone on bone movement causes polished look with sclerosis beneath

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3
Q

Osteophytes:

A

Seen in osteoarthritis: bone spur at joint edge

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4
Q

Osteoarthritis symptoms (5):

A
  • Deep achy pain
  • Morning stiffness
  • Worse with use
  • Crepitus of joint
  • Limited range of motion
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5
Q

Heberden nodes:

A

Osteophytes at DIP in women

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6
Q

Osteoarthritis spares (3):

A
  • Wrists
  • Elbows
  • Shoulders
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7
Q

Pannus (4):

A

Rheumatoid arthritis

  • Exuberant inflamed synovium
  • Chronic inflammation with T cells
  • Granulation tissue with hemosiderin
  • Erodes articular cartilage
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8
Q

Hand deformities in RA (3):

A
  • Radial deviation of wrist
  • Ulnar deviation of fingers
  • Flexion-hyperextension of fingers (swan neck; boutonniere)
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9
Q

Seronegative spondyloarthropathies (4):

A
  • Pathology in ligamentous attachments
  • Immune mediated
  • No specific autoantibody
  • HLA-B27
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10
Q

Ankylosing spondyloarthritis (3):

A
  • Young adults
  • HLA-B27
  • Axial joints
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11
Q

Reactive arthritis (3):

A

Reiter Syndrome:

  • Appendicular noninfectious arthritis
  • < 1 month after primary infection
  • Triad (see, pee, tree):
    • Arthritis
    • Urethritis
    • Conjunctivitis
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12
Q

Psoratic arthritis (3):

A
  • HLA-B27 and HLA-Cw6
  • Insidious
  • Pencil in cup deformity in DIP
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13
Q

Tophi:

A

Mass deposits of urates in gout.

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14
Q

Gout phases (4):

A
  1. Asymptomatic hyperuricemia
  2. Acute arthritis
  3. Intercritical gout (no symptoms)
  4. Chronic tophaceous gout
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15
Q

Ganglion cyst (3):

A
  • Cyst near joint or tendon sheath
  • Wrist is most common
  • No communication with joint space
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16
Q

Synovial cyst (2):

A
  • Connected to a joint or bursa

- Baker cyst: popliteal synovial cyst