J. Human Papillomavirus

Question 1

sturcture

Answer 1

has dsDNA genome. an icosahedral capsid and naled

Question 2

HPV type 16 and 18

Answer 2

cause about 70% of cervical caner

Question 3

HPY type 6 and 11

Answer 3

are not oncogenic. cause 90% of genital warts

Question 4

gardasil

Answer 4

quadravalent HPV vaccine. has anitgen from 4 diff serotypes 6,11,16,18. recombinant vaccine. major capsid proteins expressed in yeast. then purified and mixed to form vaccine produces protective humoral response