E. Viral envelope Flashcards
envelope
a layer outside the capsid. all animal viruses w/helical capsid have one. some icosohedral virus have one
viruses w/o an envelope are called
naked
envelope structure
composed of a phosholipid bilayer derived from a host cell membrane like PM. virally encoded glycoproteins inserted into bilayer called spike proteins
glycoprotein structure
composed of one or more polypeptide each w/ one or more domains. internal domain is in contact w/other viral protein. transmembrane domain is short hydrophobic helix. also external domain
external domain of glycoprotein structure
is larger than other domains, glycosylated, includes the site for binding to host cell receptors. major antigen determinant of virus, mediates fusion during entry of some viruses
overall shape of envelope virus is
spherical or pleomorphic