IV General Anesthetics

Question 1

Thiopental

Answer 1

Barbituate, poor analgesic that raidally crosses the BBB, action within 30-40 seconds. Hepatic metabolism.

Question 2

Thiopental side effects

Answer 2

Decreases CO, BP, MV. Donot give to someone who is hypovolemic or porphyria.

Question 3

Midazolam

Answer 3

Benzo. Slow rate of induction, but faster than diazempam. Moderate CV an resp depression.

Question 4

Negative side effect of using benzos (midazolam and diazepam) as general anesthetics?

Answer 4

Long time to wear off. Prevent this with flumazenil.

Question 5

Propofool

Answer 5

Used for “day surgery,” *VERY SHORT HALF-LIFE, Vasodilation causes decrease in BP.

Question 6

Fentanyl / Morphine

Answer 6

Opioids. powerful analgesic to supplemen general anesthesia. respiratory ad CV depression (not much). Nausea during recovery –> treat with naloxone.

Question 7

Etomidate

Answer 7

Does not cause CV an respiatory deression. Can use in hypovolemic patients

Question 8

Ketamine

Answer 8

Increases BP and CV output so give to people in shock or who dont have any fluids!!!!!!!!!!!!!!!!!! Binds NMDA receptors, may have hallucintions days after surgery.