ITE - Rheum

Question 1

Adult onset Still diease: Dx.

Answer 1

Dx: fever, salmon-colored rash, lymphadenopathy, leukocytosis, arthritis

Question 2

Antisynthetase syndrome: Dx.

Answer 2

Dx: Anti-aminoacyl-tRNA synthetases (anti-Jo-1)

Question 3

Cervical compressive myelopathy in RA: Tx.

Answer 3

Tx: Surgical decompression with careful intubation to prevent c1-c2 subluxation

Question 4

Limited cutaneous systemic sclerosis: Tx.

Answer 4

Tx: Methotrexate, mycophenalate, cyclophosphamide, rituximab, antihistamines, low-dose prednisone

Question 5

Mixed connective tissue disease, Dx.

Answer 5

Dx: clinical signs of 2 of: SLE, polymyositis, systemic sclerosis. Anti-U1-ribonucleoprotein Abs

Question 6

Relapsing polychondritis, Dx.

Answer 6

Dx: inflammation/damage of cartilage, especially ear, nose, large airways, joints

Question 7

RA: Dx.

Answer 7

Dx: joint disease in small joints, symmetric with RF, anti-CCP

Question 8

Sjogren syndrome ass’d lymphoma type.

Answer 8

Associated with non-hodgkin lymphoma

Question 9

SLE: Dx.

Answer 9

Dx: Skin and joint findings w/ B-symptoms. testing shows anti- dsDNA/smith/U1-ribonucleoprotein/Ro/SSA/La/SSB

Question 10

Giant cell arteritis, Dx, Tx.

Answer 10

Dx: age >50, new HA, jaw pain with chewing, visual disturbance. confirm with temporal artery bx
Tx: prednisone

Question 11

Recurrent gout, Tx.

Answer 11

Tx: pegloticase infusion, DC once stops working (i.e., Abs developed)

Question 12

Polymyalgia rheumatica, Tx.

Answer 12

Tx: low dose roids, empiric