Issues in research in clinical ethics Flashcards

1
Q

What does good science mean?

A

This is to develop a theory // paradigm // model which provides a bass for research.

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2
Q

What is ethical science?

A

A set of MORAL obligations which define right and wrong.

This relates to UNBIASED scientific knowledge.

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3
Q

What does epistemically good mean?

A

Relating to knowledge of knowing something.

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4
Q

What does publication ethics mean?

A

Rules of conduct generally agreed upon when publishing results of scientific research.
Protects the work and prevents the RE - PUBLICATION of someone’s work without PROPER CREDIT.

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5
Q

What does ‘publish and perish’ culture mean?

A

Pressure to publish in order to succeed in an academic career.

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6
Q

What does salami slicing mean?

A

Splitting data derived from a single research idea into multiple publishable units.

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7
Q

What does authorship mean?

A

Being the writer of a publication.

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8
Q

What is industry bias also known as?

A

Funding Bias.

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9
Q

What is industry bias?

A

This is a method of ways in order to get the studies skewed to a favourable result.
They fund the companies in order to produce positive results.

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10
Q

What is publication bias?

A

Tendency for investigators to submit // accept manuscripts for publication based on strength // funding of the study.
DISTORTS DATA.

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11
Q

What is self - plagiarism?

A

Using one’s OWN previous work in ANOTHER context without citing it was used previously.

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12
Q

What is peer review fraud?

A

Impersonating a peer reviewer -> making money despite being unknown and not doing any actual work.

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13
Q

In terms of animal research methods, what are animals used for?

A

Eye irritancy
Neurotoxicity
Skin sensitisation
Carcinogenicity

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14
Q

What diseases were cured via the usage of animal research?

A
Smallpox
Cancer
Malaria 
HIV / AIDS
Polio
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15
Q

What is the ‘The Animals ( Scientific Procedures) Act 1986’?

A

Protects the usage of animals for scientific purposes.

Provides special care for primates // cats // dogs // horses.

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16
Q

What are the 3 licences which must be granted in order for animal experimenting to occur?

A

Personal Licence
Project Licence
Establishment

17
Q

When was the Martin’s Act released?

A

1822

18
Q

What did the Martin’s Act address?

A

Protects animals -> cattle and horses against cruelty.

19
Q

What is another name for Martin’s Act?

A

Cruel Treatment of Cattle Act.

20
Q

How was the Martin Act amended in 1835?

A

Amended to include the protection of dogs // cats alongside other domestic animals.

21
Q

What are the 3R’s of ethical animal experimentation?

A

Reduce
Replace
Refine

22
Q

What is reduction?

A

The number of animals used should be kept to a minimum.

‘Obtain the necessary details from FEWER animals’.

23
Q

What is replacement?

A

Replace the usage of animals with alternative techniques -> avoid animal usage altogether.

24
Q

What is refinement?

A

Better housing // improvements which MINIMISE pain and suffering.