Ischemic Heart Disease Flashcards
IHD
Symptomatic coronary atherosclerotic heart disease, coronary arteries narrowed and less oxygen to the heart
Which lipid is bad
LDL
Increased level of which lipid reduces the risk
HDL
One of the most significant risk factors for IHD
Increased blood pressure
Single most important modifiable risk factor of coronary heart disease
Cigarette smoking
Physiologic injury to artery occurs when
Disturbed blood flow at bending points or bifurcations
Foam cells
Macrophages engulf lipid molecules- fatty streak
Covering of lipid debris
Collagen, fibrous covering or cap
If less collagen then
Thin fibrous capsule can rupture and lipid debris can travel through blood and cause thrombus formation
Thorasic pain, substernal, relieved by vasodilator
Angina Pectoris
Episodic chest discomfort, predictable, reproducible
Stable angina pectoris
Syndrome between stable angina and acute MI
Unstable angina
Unstable angina pain can last for up to
30 mins
Unstable angina features
-occurs at rest, lasting more than 20 mins if not interrupted by nitroglycerin
-severe, frank pain, new onset
-Crescendo pattern(more severe, prolonged, or frequent than previously)
Crushing, squeezing, heavy feeling more severe than angina. Not relived by nitroglycerin
MI
Uncommon form of angina that occurs at rest and by focal spasm of coronary artery
Prinzmetal variant angina
Biomarkers of MI
Troponin, creatine kinase isoenzyme(CK-MB)
Biomarker More sensitive and specific to heart
Troponin
Marker showing cardiac cell injury as well as skeletal muscle injury
CK -MB
Stable angina, history of MI >30 days dental considerations
-pre op and 5 min post anesthetic readings
-anxiolytic and sedative drugs
-avoid long stressful appts
-supplemental oxygen
-comfortable chair position
-availability of nitroglycerin
Unstable angina, recent history of MI dental considerations
-avoid elective tx
-refer to physician
-only tx emergencies
-all same as stable management but extra is: Administer prophylactic nitroglycerin
Drug considerations for IHD
-If pt on CCB then avoid erythromycin and clarithromycin
-NSAIDs use with caution
-do not discontinue aspirin
-minimize epi to 2 carps of 1:100,000
Avoid retraction cords with epi
Chest pain alleviated by nitroglycerin but returns then manage as
MI
Angina attack management
-Substernal pain radiating, lasts more than 15 mins
-sweating, increased heart rate and blood pressure. Pt anxious
-place in sitting up position
-CAB
-oxygen and nitroglycerin
-repeat 2 more times if pain not gone
-if pain not gone after 3 times then call 911 and give one aspirin 325 mg
Acute MI management
-crushing, squeezing pain more than 15 mins
-not gone by nitroglycerin
-cyanotic, pale, weak, cold sweat, coughing, dyspnea
If conscious
-sitting up
-CAB
-MONA:
Oxygen
Nitroglycerin
Aspirin 325mg
N2O 30%
Morphine
Nitroglycerin contraindicated when
BP less than 90/60 mm hg
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