Diabetes mellitus Flashcards
Impaired insulin secretion, hyperglycaemia , younger age of onset
DM 1
Insulin deficiency and insulin resistance. Older patients
DM 2
Overproduction and poor utilization of insulin results in over accumulation of glucose.
Hyperglycemia
Increased glucose in urine, dehydration and loss of electrolytes, nonketotic coma
Type 2 DM
Patient will eat more but still may loose weight due to cellular starvation
Diabetes Mellitus
DM type I medications
Rapid acting - Insulin aspart, insulin lispro
Short acting- regular soluble
Intermediate acting -NPH isophane, lente
DM type II medications
Sulfonylureas
Metformin
Thiazolidinediones/glitazones
Alpha-glucosidase inhibitors- acarbose, miglitol
Meglitinides- repaglinide, nateglinide
HbA1c target and optimal
Target- <= 7%
Optimal- <= 6%
Fasting plasma glucose target and optimal
Target- 4 to 7 mmol/L
Optimal - 4-6 mmol/L
2 h post prandial glucose
Target : 5-10mmol/L
Optimal: 5-8mmol/L
Dental management special considerations for diabetes
Use glucometer
For pts taking sufonylureas avoid aspirin or NSAIDs
Fasting blood glucose reading which recommends defering elective tx
<70 mg/dL or >200 mg/dL
Thirst
Excessive urination
Weakness, visual disturbances
Dry skin and heat
Fruity sweet breath odour
Kussmaul’s respiration
Diabetic coma or hyperglycemia
Hunger, nausea
Rapid weak pulse
Sweating, shaking
Slurred speech, pallor
Tonic clonic
Hypotension
Hypothermia- cold & sweaty
Hypoglycemia or insulin shock
Hypoglycemia management
Conscious:
Upright
Drink with high sugar
Monitor vital signs
Unconscious:
Supine position
911
Head tilt chin lift
Oxygen
50% dextrose IV or glucagon 1mg SC or IM