Hemophilia And Von Willebrand’s Disease

Question 1

Bleeding disorder caused by low factor VIII

Answer 1

Hemophilia A

Question 2

Bleeding disorder caused by low factor IX

Answer 2

Hemophilia B

Question 3

No spontaneous bleeding, delayed onset of bleeding after trauma surgery or extractions. 6-49% normal clotting factor

Answer 3

Mild hemophilia

Question 4

Bleeding with minor trauma, severe bleeding with surgery 1-5% normal clotting factor

Answer 4

Moderate hemophilia

Question 5

Spontaneous bleeding, excessive bleeding with trauma or surgery , <1% clotting factor

Answer 5

Severe hemophilia

Question 6

Prolonged PTT
Normal PT
Normal platelet count
Normal bleeding time

Answer 6

Hemophilia

Question 7

Post extraction treatment for all forms of hemophilia

Answer 7

Antifibrinolytic agents- tranecamic acid 25mg/kg 3 times daily for 5-7 days
Soft diet 7 days
Examine pt after 24-48 hours to check for bleeding

Question 8

Considerations for hemophilia pts

Answer 8

Avoid block,IM, lingual infiltration, injection in floor of mouth
Avoid aspirin and NSAIDS

Question 9

Mild to moderate hemophilia pts undergoing surg procedure

Answer 9

Use desmopressin, tranexamic acid or aminocaprioc acid

Question 10

Severe hemophilia pt undergoing surgery

Answer 10

Needs factor VIII replacement

Question 11

Absence of bon willebrand’s factor causes failure to form platelet plug
Prolonged PTT, prolonged bleeding time

Answer 11

Von Willebrand’s disease