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Pretest 2 > ISBB > Flashcards

ISBB Flashcards

1
Q

Chinese variolation

A

Inhale powder

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2
Q

Cook carier of typhoid

A

Mary mallon

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3
Q

Study of antibody structure

A

Geral edelmam, Rodney porter

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4
Q

Antibody diversity developed by

A

Susumu tonegawa

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5
Q

Developmental abnormality of the third and fourth pharyngeal pouches that affects thymic develoment

A

DiGeorge Anomaly

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6
Q

Small solubke proteins that regulate the immune system, orchestrating both innate immunoty and the adaptive response to infection; these chemical messengers, produced by several different types of cells, have activity-modulating effects on the hematopoietic and immune systems through activatiom of cell bound receptor proteins

A

Cytokines

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7
Q

Family of cytokines that enhance motioity and promote migration of many types of WBCs toward the source of the chemokine (chemotaxis)

A

Chemokine

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8
Q

Sedimentation coefficient of IgA, IgG, and IgD

A

7s

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9
Q

Sedimentation coefficient if IgE

A

8s

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10
Q

Sedimentation coefficient of IgM

A

19s

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11
Q

Papain fragmentation result

A

2Fab + Fc

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12
Q

Pepsin fragmentation result

A

F(ab)2 + Fc’

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13
Q

Sirface marker of NK cells

A

CD 16 & CD56

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14
Q

Proinflammatory cytokine

A

Interleukin 8

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15
Q

Most common agents are drugs and insect stings

A

Anaphylactic reactions

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16
Q

Most common congenital immunodeficiency

A

Selective IgA deficiency

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17
Q

Severe recurrent infections, glumerulonephritis

A

C3 deficiency

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18
Q

Lupuslike syndrome, recurrent infection, atherosclerosis

A

C2 deficiency

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19
Q

DAF, CD59 (MIRL) deficiency

A

PNH

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20
Q

HLA-B27 is seen in

A

Ankylosing spondylitis

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21
Q

Mixed lymphocyte reaction is in what test

A

Cellular assay

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22
Q

Most specific antibody for SLE

A

Anti-dsDNA

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23
Q

HRP-2 antigen

A

P. Falciparum

24
Q

Dil. Household bleach prepared daily inactivates HBV within

A

10 mins

25
Q

Dil. Household bleach daily inactivates HIV within

A

2 mins

26
Q

HLA antigen detection using

A

Microlymphocytotoxic test

27
Q

Fluorescenancintense apple-green color

A

Fluorescein

28
Q

Fluoresce an orange-red color

A

Rhodamine

29
Q

EDTA-anticoagulated amples are preferred (pink , purple)

A

DAT, Direct AHG Test

30
Q

ISBT 001

A

ABO

31
Q

Greatest to least amount of H antigen

A

O>A2>B>A2B>A1>A1B

32
Q

Anti- A1 lectin

A

Dolichos biflorus

33
Q

Anti-H lectin

A

Ulex europeaus

34
Q

Antigens passively adsorbed onto the RBC membrane from the plasma

A

Lewis antigen

35
Q

Diminished on the mother’s RBCs during pregnancy

A

Lewis antigen

36
Q

HLA on red cells

A

Bg, Bennett - Goodspeed

37
Q

Associated wifh C4

A

Chido, Rodgers

38
Q

Cold agglutinins in the serum of normal individuals and in patients with acquired hemolytic anemia; Wiener and coworkers, gave a name to one such agglutinin, calling its antigen “I” for individualit. The antibody reacted to most blood specimens tested

A

Anti-I

39
Q

Found in renal patients dialyzed with formaldehyde sterilized equipment

A

Anti-N like antibody

40
Q

Produce by S-s-u (-), Blacks

A

Anti-U

41
Q

Safest blood a recipient can receive is his or her own blood

A

Autologous transfusion

42
Q

Shelf life of blood stored with COD-A1

A

35 days

43
Q

Whole blood from which cryoprecipitate and/or platelets have been removed

A

Modified whole blood

44
Q

Preparation of leukopoor RBCs

A

Centifugation, filtration, saline-washing

45
Q

Components of cryoprecipitate

A

Fibrinogen (150 mg)
AHF (80 Units)
vWF
Factor XIII

46
Q

Indication of irradiated blood comonents

A

Prevention of TA-GVHD, inactivate T cells

47
Q

Facilitate oxygen transfer into the platelet bag and oxygen consumption by platelets

A

Platelet agitation

48
Q

Synthetic vasopressin analogue that can stimulate release of vWF

A

DDAVP (desmopressin)

49
Q

Associated with posttransfusion hepatitis of unknown etiology (nonA-G). After the initials of the first patient from who, the girus was isolated (TT)

A

TTV

50
Q

Due to anti-leukocyte antibodies, leukoreduced blood components should be used

A

Transfusion-associated acute lung injury (TRALI) or noncardiogenic pulmojary edema (NCPE)

51
Q

Iatrogenic, physician caused
At risk are children, elderly patients and patients with normovolemic anemia, cardiac disease,cthalassemia major or sickle cell disease

A

Circulatory overload

52
Q

Transfusion hemosiderosis
Accumulation of iron in heart, liver, and endocrine glands
At risk are the transfusion-dependent patients: cingenital hemolytic anemia, aplastic anemia and chronic renal fialure

A

Iron overload

53
Q

Young RBCs, longet lifespan

A

Neocytes

54
Q

Major cause of transfusion associated fatalaties

A

Clerical error

55
Q

Primary advantage of gel technology

A

Standardization

Pretest 2 (7 decks)

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