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MTAP 2 BABY > IS HLAs > Flashcards

IS HLAs Flashcards

1
Q

HLA-B27

A

Ankylosing Spondylitis

Reiter’s syndrome

Juvenile RA

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2
Q

HLA-DR4

A

RA
IgA neuropathy
Type 1 diabetes

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3
Q

HLA-DR3

A

Sjorgen’s syndrome
Gluten Sensitive Enteropathy
Chronic active hepatitis
Dermatitis Herpetiformis
Idiopathic membranous glomerulonephritis
Grave’s disease
Dermatitis Herpetiformis

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4
Q

HLA-DR2/DR3

A

SLE

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5
Q

HLA-B5

A

Ulcerative colitis

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6
Q

HLA-A3, B14

A

Idiopathic Hemochromatosis

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7
Q

HLA-DR5

A

Pernicious anemia
Hashimoto’s disease

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8
Q

HLA-B13, HLA-Cw6

A

Psoriasis Vulgaris

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9
Q

HLA-B5

A

Bechet’s Disease

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10
Q

HLA-Dw3

A

Addison’s disease

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11
Q

HLA-B8

A

Myasthenia gravis

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12
Q

HLA-DR2

A

Multiple sclerosis

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13
Q

HLA-A28

A

Schizopernia

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14
Q

Mediator of innate immune response

A

IL-1

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15
Q

Acts as antagonist to IL-1 by blocking the IL-1 receptor and limiting availability of the receptor for IL-1

A

IL-1RA

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16
Q

Principal mediator of the acute inflammatory response to GN bacteria

A

TNF

17
Q

Cachectin
Most prominent member of TNF

A

TNF-A

18
Q

TNF-A is secreted by

A

activated monocytes and macrophages

19
Q

Lymphotoxin

A

TNF-B

20
Q

Factors that induced growth arrest in tumor cells

A

TGF-B

21
Q

Interfere with viral replication process in an infected cells

A

Interferon

22
Q

IFN-a is produced by

A

Mononuclear phagocytes

23
Q

IFN-b is produced by

A

Fibroblast and epithelial cells

24
Q

IFN-Y is produced by

A

TH1 cells

25
Q

Antagonist to IL-4
Major macrophage activator
Stimulates antigen presentation by Class II MHC

A

IFN-Y

26
Q

Drives the growth and differentiation of both T and B cells and induces lytic activity in NK cells
T-cell growth factor

A

IL-2

27
Q

Responsible in allergic reaction, parasitic infections, and auto immune disease

Induces T-CELL PROLIFERATION

A

IL-4

28
Q

Inhibits production of pro-inflammatory cytokines by mononuclear phagocytes

Inhibits the accessory functions of mononuclear phagocytes for T cells activation

acts as an antagonist of IFN-Y

A

IL-10

29
Q

Induces hematopoiesis

A

IL-3

30
Q
A

MTAP 2 BABY (7 decks)

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