IRON

Question 1

List the distribution of iron storage in the body

Answer 1

70% of the body’s iron is found in RBC
6% is a component of certain essential proteins required for respiration, energy metabolism and enzymes
25 % is stored as ferritin and Hemosiderin, cytochrome, hemoproteins etc
2.2 % is found in labile poil

Question 2

What is a labile pool

Answer 2

A poorly defined and reactive pool of iron that forms ROS( free radicals) via the Fenton reaction which forms complexes with a drug known as Chelators

Question 3

——– mg of ferrous sulfate needs to be consumed to give the RDA

Answer 3

325 mg

Question 4

Absorption of iron occurs in the ?

Answer 4

Duodenum and proximal jejenum

Question 5

The enzyme bound to the apical membrane to apical membrane of enterocytes is

Answer 5

Dcyt b duodenal cytochrome b

Question 6

What is DMT 1

Answer 6

Divalent metal cation transport 1

Question 7

What is the function of feroxidase?

Answer 7

It allows the mobilisation of fe2+ out of ferrihydrite mineral lattice structure.

Question 8

What is apoferritin and what is its function?

Answer 8

Ferritin that is not bound to iron and has an intrinsic catalytic activity of converting ferrous iron to ferric iron

Question 9

Iron is made in the body T/F

Answer 9

False

Question 10

Only —- to—– % of iron is absorbed

Answer 10

10-30%