Fat Synthesis Etc Flashcards

1
Q

What is fat?

A

Fat is a long-chain hydrocarbon containing carboxylic acid moiety at one end

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2
Q

Most naturally occurring fat exist in ………. With ……… Being the most common

A

C4-C22
C18 is the most common

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3
Q

How do the following affect the melting point of fat?
Number of carbons
Degree of unsaturation

A

The higher the number of carbons the higher the melting point.
The higher the point of unsaturation,the lesser

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4
Q

Saturated Fat with less than 8 no of carbon is ……….. at room temp while >10 is

A

Liquid
Solid

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5
Q

Most naturally occurring unsaturated fatty acid exists in

A

Cis form

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6
Q

Trans fat is found in

A

Food
Hydrogenation of unsaturated FA

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7
Q

Essential fatty acids with the site of unsaturation beyond carbon ….. and …… cannot be synthesised in the body
List

A

9 and 10
Linoleic18: 9,12
Linolenic 18:9,12,15
Arachidonic20: 5,811,14
Eicosapentaenoic ( EPA) 20: 5,8,11,1417
Docosahexaenoic acid ( DHA) 22:
6 sites of unsaturation starting from 4

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8
Q

Most common fatty acids are

A

C16 and C18

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9
Q

Citrate shuttle is made up of

A

Tricarboxylate translocase system

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10
Q

The enzymes for elongation are called ?

A

Elongases ( thiolase)

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11
Q

Elongation takes place in ………..

A

Mitochondria and Endoplasmic reticulum

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12
Q

Elongases prefer fatty acids of ………… Carbons

A

16 carbons or less

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13
Q

The major substrate of elongation is ……….

A

Stearoyl Co A

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14
Q

Desaturation occurs where?

A

Endoplasmic reticulum

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15
Q

Desaturases uses oxygen as ……..

A

Electron acceptor

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16
Q

Desaturases introduce double bonds at positons

A

9,6,5

17
Q

The two common naturally occurring fatty acids are

A

Palmitoleic 16:1d9
Oleic 18:1d9

18
Q

Animals cannot synthesize linoleate or linolenate fatty acids because?

A

They lack desaturases that can introduce a double bond beyond carbon 9

19
Q

Mammals can synthesize arachidonic acid but plants cannot T/F

A

True

20
Q

Arachidonic acid is a precursor for group of enzymes called

A

Eicosanoids