Ipratropium Bromide

Question 1

What is the generic name for Ipratropium Bromide?

Answer 1

Ipratropium Bromide Monohydrate

Question 2

What brand of Ipratropium Bromide is used by NSW Ambulance?

Answer 2

Atrovent

Question 3

What type of medication is Ipratropium Bromide?

Answer 3

An Anticholinergic Bronchodilator. It blocks the parasympathetic nerve reflexes that cause the airway muscles to constrict by opposing the action of the neurotransmitter Acetylcholine.

Question 4

What are the actions of Ipratropium Bromide?

Answer 4

Bronchodilation.

Blocks vagal reflexes which mediate bronchoconstriction.

Synergistic when used in combination with Salbutamol (Ventolin).

Question 5

What is the route for Ipratropium Bromide administration, and the associated onset, peak and duration?

Answer 5

NEB: onset 3-5min, peak N/A, duration 2-4hrs.

Question 6

What conditions indicate administration of Ipratropium Bromide?

Answer 6

Asthma.

COPD exacerbation.

Question 7

What are the adverse effects of Ipratropium Bromide?

Answer 7

Mild anticholinergic effects, e.g. urinary retention, dry mouth, blurred vision, pupil dilation.

Question 8

What are the contraindications of Ipratropium Bromide?

Answer 8

Allergy or hypersensitivity to Ipratropium Bromide.

Glaucoma.

Question 9

What is the appropriate dose of Ipratropium Bromide for Asthma/COPD?

Answer 9

If the patient is <6yrs old, the correct dose is one 250mcg in 1ml nebule administered via nebuliser, with one repeat for a max dose of 500mcg.
If the patient is 6yrs or older, the correct dose is one 500mcg in 1ml nebule administered via nebuliser, with one repeat for a max dose of 1mg.