IOTA 15

Question 1

What are the 2 barriers in the brain

Answer 1

Blood CSF barrier -due to tight junctions

Blood brain barrier - due to tight junctions in capillary epithelium

Question 2

What is the role of tight junctions in the brain?

Answer 2

Protect the brain

Damage= disease

Question 3

What is the function of the Blood CSF brain barrier ?

I

Answer 3

It is a secretory structure: Produce CSF-200mls NON STATIONARY- FLOWS AT 500MLS PER DAY

20 ml is found in the ventricles ( R,L,3,4 (lateral ventricles ))

180 mls in sub arachnoid space and cisterns

Question 4

CSF can cross in both directions of what barrier?

Answer 4

Ependyma

Via concentration and pressure gradient

Question 5

Where do you have the development of toxins and co2?

Answer 5

Interstitial fluid

Question 6

Where is the Choroid plexus found?

Answer 6

In right and left lateral, third, and fourth ventricles

Question 7

Where is the third ventricle found?

Answer 7

Diencephalon

Question 8

Number 1 excitatory neurotransmitter in CNS

Answer 8

GLUTAMATE

Question 9

Arachnoid and Pia mater together are called?

Answer 9

LEPTOMENINGES

Question 10

Choroid plexus is formed by?

Answer 10

Choroid epithelium (has tight junctions) + Choroid capillary

Question 11

Ependyma cells?

Answer 11

Have no tight junctions