Iodine revision - week 12

Question 1

Absorbed

Answer 1

• in SI

- Goitrogens food decrease idoine availability for absorption e.g. turnips, cabbage, brussel sprouts, broccoli

Question 2

Transported

Answer 2

• Bound to thyroglobulin, taken to the thyroid gland

- Sodium dependent transport system traps iodine in thyroid gland for hormone synthesis

Question 3

Stored

Answer 3

Muscle, thyroid gland, skin, bone

Question 4

Excreted

Answer 4

via kidney/urine

Question 5

Major function

Answer 5

• Component of thyroid hormones that regulate basal metabolism, growth, and development, and energy metabolism
• T3 (active hormone form) and T4 (thyroid hormone in circulation) – T4 converted to T3 by DIOs

Question 6

food sources

Answer 6

iodized salt, seaweed, dairy product

Question 7

deficency

Answer 7

• Goiter – T4 levels drop ->increase TSH secretion ->thyroid enlarges to trap more iodine ->slow metabolism
• neurological cretinism – irreversible mental retardation, loss of hearing or speech abilities, short stature

Question 8

toxicity

Answer 8

• Inhibition of function of the thyroid gland (enlarged) – hypothyroidism and hyperthyroidism
• Autoimmune disease
• Thyroid cancer