Introduction to Pharmacy III My notes

Question 1

Drug Information Sources
Institutions will have their own specific resources or hospital specific they may be policies or procedures or they may be guidelines that the institution has compiled like Umass memorial has both a Renal Dosing handbook and pharmacy to dose protocols that institution specific

Question 2

Hospital Specific:
Example: IV Medication Administration Guideline which dictates how fast medication can be run over or which floors medications floors can be administered on
Cons: Renal dosing handbook might not have every medication that requires renal dosing it will have the most common ones but it not have everything that requires renal dosing

Question 3

Lexidrug has hospital formulary will tell you what formulation the institution carries and if the medication is restricted or has certain guidelines that needs to be followed and for the pharmacists and providers to be on the same page because everyone can look at that at the same resources

Question 4

Lexidrug has a lot of different breakdowns and sidebar buttons so you need to know where to look for certain things so that’s one of the downsides

Question 5

UptoDate seems to be more disease state base as opposed to medication specific

Question 6

UptoDate does not include specifics so when speaking about medications it might recommend a specific medication but it won’t say specific dosing so that’s one of the drawbacks

Question 7

Lexidrug and UptoDate are both run by the same company so they are integrated into each other so that is a perk of using these two systems where both the medications are integrated into a resource like UptoDate that’s provided these general overviews

Question 8

Clinical Pharmacology only resource that allows for clinical comparison you can type in two different medications that you want to compare and you want to compare their uses or their dosing and do a side by side and compare those two medications although you will see many of these clinical resources due include monitoring parameters in some form…clinical pharmacology does so in a nice bulleted list so it makes it very easy to refer to and look at quickly and refer back to

Question 9

Trissels is integrated into Lexicomp so that does include IV compatibility but its not within the specific drug pages itself you have to go specifically to Trissels within Lexicomp whereas clinical pharmacology you can see IV compatibility right where you see drug monograph page.

Question 10

Micromedex has info on Neonates=newborn babies

Question 11

When you are trying to pull a drug monograph and you just type in the medication name to do so there’s usually quite a long list depending on what medication your looking at that comes up and you have to look through and see which one is the right one you need to click at to open that drug monograph where is if you are searching something like Lexicomp there’s really only one or two medications to pick from if you type in the fullname and do so correctly so something else to keep in mind when we are looking at these resources

Question 12

St.john’s wort, garlic, ginger root you can look at Natural Medicines resources it can tell you if something is likely safe, possibly safe,rating scale on its effectiveness as a supplement

Question 13

If we are doing dosing calculations we need to use exact metric equivalent to make sure patients are being dosed correctly

Question 14

Vancomycin is an IV antibiotic

Question 15

TPN=total parenteral nutrition…parenteral means given through IV

Question 16

Vancomycin…loading dose may be the same as maintenance dose in other words pt might get started on one particular dose and continue that until we can get levels to monitor this antibiotic or they might get an initial dose…their first dose that’s given at a higher dose also known as a loading dose to start regimen and help get the patient to reach therapeutic levels faster so we need to keep in mind what type of protocol we are following when we are dosing this medication and not only is vancomycin a weight based dose but the frequency of the medication is going to account for the patient’s renal function

Question 17

Round 250mg so we don’t waste vials when the medication is being compounded…once we have our dose we also need to determine our frequency this is based on the patient’s creatinine clearance so we need to calculate our patient’s creatinine clearance based on serum creatinine, age, weight, and height in order to determine how frequently the medication can be given so if they have great creatinine clearance like greater than a 100 we can start pt on every 8 hrs

Question 18

Morphine,Hydromorphone, and fentanyl are available IV