Introduction to Nervous System Flashcards
Describe the structure of a neuron
Cell Body (also called a SOMA)
Neurites - axons/dendrites
Describe an axon
Single
Usually covered with Myelin or Schwann sheath
Describe a dendrite
Multiple
Thin, short extensions
Are there more neurons or glial cells ?
Glial cells
What is a major advantage of glial cells vs neurons ?
Glial cells can regenerate whilst neurons cannot.
Name the 2 glial cells involved in the PNS
Satellite cells
Schwann cells
Name the 4 glial cells involved in the CNS
Oligodendrocytes
Astrocytes
Microglia
Ependymal cells
Function of Satellite cells
Support the cell body (SOMA)
Function of Schwann cells
Myelin production in the PNS
Function of Oligodendrocytes
Myelin production in the CNS
Function of Astrocytes
+BBB
Function of Microglia
Scavengers
Function of Ependymal cells
CSF production
What is myelin ?
Insulation material
Rich in lipid and proteins
Function of myelin sheath
Makes conduction faster, requiring less energy
What types of neuroglia produce myelin ?
Schwann cells - PNS
Oligodendrocytes - CNS
Explain how Schwann cells surround the axon
The Schwann cells have a nucleus and cytoplasm.
They surround the axon by wrapping around them (Engulfing the axon)
The Schwann cells produce the myelin sheath.
Difference between Schwann cells and oligodendrocytes
Oligodendrocytes produce myelin for a number of axons, whereas Schwann is for one axon.
Oligodendrocytes are progenitor derived.
Schwann cells are neural crest derived.
How do neurons communicate ?
Via synapses
Communication is established by various neurotransmitters.
Where are neurotransmitters found ?
In vesicles in the synapse of an axon
What is a ganglion ?
A structure containing nerve cell bodies outside the CNS.
What is the gap between 2 neurones called ?
Synaptic cleft
What do the neurotransmitters bind to ?
The receptors on the next neurone.
What is a nucleus in nervous system ?
A structure containing nerve cell bodies inside the CNS.
What are the 2 major components on the nervous system ?
Gray matter
White matter
What is gray matter ?
Predominantly cell bodies of neurons and neuroglia and unmyelinated neurites
Where is gray matter found ?
On the surface of the cerebral hemispheres as well as the depths of the cerebrum.
In the brain where is the gray and white matter ?
Gray - outside
White - inside
In the spinal cord where is the gray and white matter ?
Gray - inside
White - outside
What is white matter ?
Axons - usually myelinated
Up/Down - blue
Projection fibres
Front/Back - green
Association fibres
Left/Right - red
Commissural fibres