Intro To Pharmacology Flashcards
Airborne precautions
Essential when dealing with airborne pathogens; eyewear, N95, shield, gloves
Contact precautions
Protective clothing and gear to minimize contamination; eyewear, gown, gloves, N95 mask
Droplet precautions
Protective clothing and gear that prevents/minimizes contamination; eyewear, gown, gloves, N95 mask, possible shield
Orphan drug act
Passed to motivate development and provision of new, effective drugs for rare diseases
Five main sources of drugs
Plants, animals/humans, minerals/mineral products, laboratory-produces chemicals, DNA-produces drugs
Drug approval process
Animals studies, clinical trials
Animal studies
Tested on at least 2 animal species; successful move to clinical trials
Clinical trials - phase 1
Tested in healthy volunteers to compare with animal data, safe doses
Clinical trials - phase 2
50 - 300 patients in a double blind studies
Clinical trials - phase 3
Larger patient group (1000s) lasting several years to evaluate efficiency and side effects
Clinical trials - phase 4
“New drug submission” to HPFB
Chemical drug nomenclature
States its chemical composition and molecular structure
Generic drug nomenclature
Should not be capitalized, available for use by other drug companies, based on drugs chemical composition; hydrochloride
Trade drug nomenclature
Manufacturer registered a drug using a trademark, sometimes called brand name, always capitalized; Demerol
Drug standardization
Drug must be uniform and consistent in strength when offered on the market