Intro to HIV Flashcards
1
Q
When was HIV first discovered in SA?
A
in 1983
2
Q
What subtypes make up the 2 HIV epidemics in SA?
A
Subtypes B and C
3
Q
Different ways of measuring HIV prevalence in SA?
A
- antenatal clinics
- household surveys
- specific groups
4
Q
3 phases of HIV
A
- acute phase
- chronic phase
- AIDS
5
Q
Common symptoms of acute HIV infection
A
- fever
- skin rash
- oral ulcers
- lymphadenopathy
6
Q
When is set-point viral load set?
A
4-6 months
7
Q
Sequence of immune responses in HIV infection
A
- acute phase reactants
- onset of cytokines
- antibody-viral immune complexes
- CD8+ T cell recognises original virus
- free gp41- specific non-neutralising IgM antibody
- virus escape from CD8+ T cells
- Autologous virus-specific neutralizing antibody
- virus escape from autologous- virus-specific neutralizing antibody
