intro

Question 1

small molecule drugs

Answer 1

• commonly used
• simple and cheap
• easy to store
• membrane permeable
• usually oral
• hit multiple receptors and cause side effects
• cause DDIs
• can cause toxicity
• extensive metabolism

Question 2

biological drugs

Answer 2

• insulin, cytokines, antibodies
• domain of biotechnology
• heat sensitive
• membrane impermeable
• need injection
• specific for one receptor
• can cause allergic effects
• rarely cause DDIs
• undergo minimal metabolism

Question 3

4 drug target proteins

Answer 3

• receptors
• ion channels
• enzymes
• transport/carrier molecules

Question 4

two types ion channels

Answer 4

ligand gated

voltage gated