intro Flashcards
1
Q
small molecule drugs
A
- commonly used
- simple and cheap
- easy to store
- membrane permeable
- usually oral
- hit multiple receptors and cause side effects
- cause DDIs
- can cause toxicity
- extensive metabolism
2
Q
biological drugs
A
- insulin, cytokines, antibodies
- domain of biotechnology
- heat sensitive
- membrane impermeable
- need injection
- specific for one receptor
- can cause allergic effects
- rarely cause DDIs
- undergo minimal metabolism
3
Q
4 drug target proteins
A
- receptors
- ion channels
- enzymes
- transport/carrier molecules
4
Q
two types ion channels
A
ligand gated
voltage gated