Intro Flashcards

1
Q

Scope of pathology

A

The cause of the disease
The mechanism of the disease
The effect of the disease on other organs

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2
Q

Subdivisions

A

Histopathology
Cytopathology
Haematology

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3
Q

Histopathology

A

Investigation and diagnosis of a disease from examination of tissues

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4
Q

Forensic pathology

A

Cause and sequence of death under suspicious circumstances

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5
Q

Surgical

A

Examination of biopsy taken surgically from a body

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6
Q

Cytopathology

A

Examination of isolated cell due to shedding into body fluid

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7
Q

Haematology

A

Disease of the blood(cellular and coagulative components)

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8
Q

Chemical pathology

A

the study & diagnosis of disease from the chemical changes in tissues & fluids

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9
Q

Properties of an Ideal Fixative

A

Prevents autolysis and bacterial decomposition
Preserves tissue in their natural state and fix all components
Preserves tissue volume
Avoid excessive hardness of tissue
Allows enhanced staining of tissue
Should be non-toxic and non-allergic for user

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10
Q

Tissue fixative

A

Formaldehyde
Gluteraldehyde
Zenker’s formal saline
Bowen’s fluid

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11
Q

Cytological fixative

A

Ethanol
Methanol
Ether

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12
Q

Histochemical fixative

A

Formal saline
Cold acetone
Absolute alcohol

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13
Q

The duration for which tissues are kept in each strength of alcohol depends upon

A

the size of tissue
fixative used
type of tissue

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14
Q

Clearing reagents

A
Xylene 
Chloroform 
Benzene
Carbon tetrachloride 
Toluene
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15
Q

Types of Wax employed for Impregnation

A

Paraffin wax

Water soluble wax

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16
Q

Toxicology

A

the study of the effects of known

or suspected poisons

17
Q

Techniques of pathology

A
Light microscopy
Histochemistry
Immunohistochemistry
Electron microscopy
Biochemical 
Haematology
Molecular
18
Q

Biopsies

A

samples of tissue removed from a patient for diagnostic purposes.

19
Q

the whole or part of an organ removed for a previously diagnosed condition.

A

Resections specimens

20
Q

Types of biopsy

A

Incision, Endoscopy, Needle

21
Q

Cytology

A

involves the examination and interpretation of dispersed cells rather than solid tissues,usually for the diagnosis of cancer & pre-cancerous lesions

22
Q

Exfoliative cytology:

A

cells shed from, or scraped or brushed off ,an epithelial surface

23
Q

Fluid cytology

A

cells withdrawn with the fluid in which they are suspended

24
Q

Washings

A

cells flushed out of an organ using an irrigating fluid

25
Q

Fine –needle aspiration cytology

A

cells sucked out of a solid tissue using a thin needle attached to a syringe.

26
Q

Autopsies are used for

A

-determining the cause of death
-audit of the accuracy of clinical diagnosis
-education of undergraduates &
postgraduates.