INTRACERLLULAR COMMUNICATION Flashcards

1
Q

can be defined as the communication that
takes place within the cell.

A

Intracellular communication

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2
Q

The basis for the coordination of the physiological functions within a
multicellular organism is

A

intercellular signaling

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3
Q

Cells communicate through chemical signals, these chemical signals are
known as

A

ligands.

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4
Q

also called lipid-soluble ligands, can directly diffuse
through the plasma membrane and interact with internal receptors.

A

hydrophobic ligands

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5
Q

bind to the
extracellular domain of cell-surface receptors.

A

Water-soluble ligands

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6
Q

within the target cell must be coordinated, fine-tuned
and channeled within a network of intracellular signaling paths that finally
trigger distinct biochemical reactions and thus determine the specific functions
of a cell

A

Signal transduction

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7
Q

Tool for Intracellular Signaling (2)

A

Extracellular messengers
Gap junctions

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8
Q

Cells send out signals in the form of specific
messenger molecules that the target cell transmits into a biochemical
reaction.

A

Extracellular messengers

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9
Q

are channels that connect
two neighboring cells to allow a direct exchange of metabolites and signaling
molecules between the cells.

A

Gap junctions

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10
Q

Tool for Intracellular Signaling (2)

A

Cell–cell interaction via cell-surface proteins

Electrical signaling

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11
Q

A further intercellular communication mechanism relies
on electrical processes.

A

Electrical signaling

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12
Q

Another form of direct
communication between cells occurs with the help of surface proteins.

A

Cell–cell interaction via cell-surface proteins

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13
Q

Features of Cell Signaling (4)

A

Specificity
Amplification
Desensitization
Integration

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14
Q

the complementarity of structure between ligand and receptor binding contributes to the high specificity of the signaling pathway.

A

Specificity

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15
Q

During intracellular communication, the signal amplifies
several folds to generate the response.

A

Amplification

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16
Q

Also known as adaption, it is the condition that arises due to the continuous binding of the ligand to the receptor

A

Desensitization

17
Q

It can be defined as the ability of the system to receive multiple
signals and produce a unified response appropriate to the needs of the cell.

A

Integration

18
Q

Stages of Intracellular
Communication (3)

A

Reception
Transduction
Response

19
Q

It refers to receiving
the signal via ligand molecule
binding to the receptor.

A

Reception

20
Q

It refers to the
transfer of the signal from the cell surface to the interior of the cell, it is achieved by activating several proteins via phosphorylation,
dephosphorylation.

A

Transduction

21
Q

A cell generates a
varying type of response according to the need, which result is the change in the metabolic activity of the cell.

A

Response

22
Q

Forms of Cellular
Signaling (4)

A

Paracrine Signaling
Autocrine Signaling
Endocrine Signaling
Direct Cell Signaling

23
Q

Signals that act locally
between cells that are close
together

A

Paracrine Signaling

24
Q

a type of signaling where the
cell releases a chemical
molecule, which acts as a
ligand that binds to the
receptor on the cell that
produces it

A

Autocrine Signaling

25
Q

It is a long-distance signaling
pathway.

A

Endocrine Signaling

26
Q

The ligands released in
endocrine signaling are
called

A

hormones

27
Q

Gap junctions in animals and
plasmodesmata in plants are
connections between the
plasma membranes of
neighboring cells.

A

Direct Cell Signaling

28
Q

Types of Receptors (5)

A

Cell Surface Receptor
Enzyme Linked Receptor
Ion Channel Linked Receptor
G – Protein Linked Receptor
Internal Receptor

29
Q

also known as transmembrane
receptors, are integral proteins that
bind to external signaling molecules.

A

Cell Surface Receptor

30
Q

are cell surface receptors with intracellular
domains that are associated with an
enzyme.

A

Enzyme-linked receptors

31
Q

bind to a ligand and open a
channel through the
membrane that allows specific
ions to pass through.

A

Ion Channel Linked Receptor

32
Q

bind to a ligand and activate an associated G-protein

A

G – Protein Linked Receptor

33
Q

also known as intracellular or
cytoplasmic receptors, are found in the cytoplasm of target cells and respond to hydrophobic ligand molecules that are able to travel across the plasma membrane

A

Internal Receptor

34
Q

Signaling Pathways and
Signal Amplification (3)

A

Signaling Pathway
Phosphorylation
Second Messengers

35
Q

After the ligand binds to the cell-surface
receptor, the activation of the receptor’s
intracellular components sets off a chain
of events that is called a

A

Signaling Pathway

36
Q

One of the most common chemical modifications that occurs in signaling pathways is the addition of a phosphate group to a molecule in a process called
phosphorylation.

A

Phosphorylation

37
Q

The transfer of the phosphate is catalyzed
by an enzyme called a

A

kinase.

38
Q

are small molecules that propagate a signal after it has been initiated by the binding of the signaling molecule to the receptor.

A

Second Messengers

39
Q

The first messenger activates a Gprotein-linked receptor, which activates
a specific G protein.

A

Cyclic AMP (cyclic adenosine monophosphate)