interventionaloncology Flashcards
what are the basic principals of thermal and cryo ablation
delivery of cold to the tumor result in in ice formation and death of the cell, advantages over thermal is that you can monitor the ablation zone during disadvantage, cryoshock leading to hypotension CIC multiorgan failure
what is the history of stage 1 renal cell cancer
tumor less than 4 cm, treatment of choice laproscopic nephrctormy 97% 5 year cancer rate,
what is the role of guided therapy in renal cell cancer
gives us a knowledge of what type of tumor it is. And lets us know where we are during the treatments.
what is the natural history of hepatocellular carcinoma
90% in cirradics, very common in Asia Hep B. doubled in us since 1980, hep c in the us,
what is the therapy of a hepatocellular carcinoma
transplants milan cirteria one tumor less than 5cm ro three but less than 3 combined, resection only in non-cirrhotic liver, systemic chemotherapy, local regional therapy. Main way in this local regional therapy.
what is are the basic principles and diffences between chemoebolization radioembolizatoin and drug eluding bead embolization
chemo is done as an oil, drug eluting bead embolization 300-700 micron beads loaded with doxorubine or similar drug to kill the tumor, radiofruency/microwave ablation deliver a friction heat and resulting in death.
how does the blood flow of the vasculuar relate to the transarterial embolization
what is transarterial chemoembolization or TACE. Highly concentrated chemotherapy in lipid medium results in tissue hypoxia and death, uses the duel blood supply able to concentrate the chomotherapy up to 40x. Tumors use the hepatic arterial blood exclusively so if you cut of the supply with an oil it will die,. Side effects are postembolization, vomiting, abdominal pain, fever, anorexia, fatigue, occurs in 90% of patients, persists for up to 14 days but usally 5
what are the implication of malignant pleural effusions and malignant ascites
occure in 15% of patients, poor prognosis life expectancy 4 months, most common in lung breast and ovarian
what is the role of radiology in management of pleural effusion and malignant ascites
periodic throa/paracentesis, chest tube with chemicle pleurodesis, or tunneled pleural peritoneal cather placement for home fluid drainage, some complication are celuulaites malfunction empyema.
tell me about radioembolization
used of intra-arterially delivered micrhoshpere emitting high dose of radiation for treatment of unresectable liver tumors lodge in microvascular of the tumor and minimizing radiation exposure to the liver, used for HCC and mtastatic colorectal cancer and is outpatient. Side effect fatigue but still can get post ratioembolization syndrom.
