bloodgroupcompatiblility Flashcards
what are the four main blood group in the abo system
A, B, AB, and O just H is O and N is A and D is B
what are the two main naturally occurring antibodies to red cell antigens
IgG and IgM but the IgG is the main one
know how to tell what antibodies would be found in each ABO group and why they would or would not be present.
as an A type you make anti B as a B type anti A as an O type you make anti AB and as an AB you make nothing
Why is the ABO system the most important red cell blood group system for transfusion therapy.
because a mismatch will cause intravascular hemolysis and is deadly.
when is a mother at risk for hemolytic disease of the fetus or newborn. HDFN why do some classes of RH cause it and others do not
Caused by IgG because it can cross the placenta, if mom has antibody againstg a red cell antigen that fetus possesses, IE mom is D negative and baby is D positive can cause abortion, so give mom anti D at 28 weeks and after delivery so she will not make the antibody herself, hurts the second child more. Not usually with ABO more with the RH antigen. given GhoGAM.
be able to diagram the DAT direct antiglobulin test, main component and source, what does it detect,
called COOMBS test, what is attached to the red blood cells, add antihemoglobulin reagents and look for agglutination invitro looking for autoantibodies
diagram the indirect antiglobulin test IAT and what is it used for.
this is looking for serum antibodies that are autoimmune,
what are the three essential steps in blood compatibility testing and why we do each step.
blood type, antibody screen, crossmatch where we mix them and see if they agglutinate.
what blood type is given in an emergency situation
RBC’s universal donor ois O and, AB is the universal donor of PLASMA. So we give them O+ to a male women it depends.
