Interstitial Lung Disease Flashcards

1
Q

Pathophysiology

A

group of conditions that affect the interstitium (lung tissue between the alveolar epithelium and the capillary endothelium) of the lungs
excessive healing - inflammatory response to injury leads to fibrosis and interstitial thickening
possible destruction of the capillary bed
resultant pulmonary HTN right sided heart failure
deconditioning results in peripheral muscle dysfunction

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2
Q

Clinical Implications

A
reduced lung volumes 
impaired gas exchange 
airflow limitation 
dyspnoea 
reduced exercise tolerance 
musculoskeletal dysfunction
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3
Q

Clinical Features

A
dyspnoea with exertion 
dry, persistent cough 
fine inspiratory crackles on auscultation 
possible finger clubbing 
spirometry - has restrictive pattern 
very low SpO2
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4
Q

Medical Management

A

supportive care (not much evidence for inhaled therapies)

  • pulmonary rehab
  • O2 therapy
  • lung transplant
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5
Q

Physio Management

A
  • pulmonary rehab
  • optimise conditions for transplant
  • NIV - most likely patients won’t be able to handle the back pressure
  • assessment to guide medical management
  • management of breathlessness
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