Interstitial Lung Disease Flashcards
1
Q
What is the most common form of ILD?
A
Idiopathic pulmonary fibrosis
2
Q
What is IPF characterised by?
A
Scar tissue formation within the lungs, dyspnoea and a significantly reduced lifespan
3
Q
What are the occupation caused forms of ILD?
A
Asbestosis (ship workers, plumbers) Silicosis Coal workers Pigeon workers/fanciers Hypersensitivity pneumonitis
4
Q
What are the diseases associated with ILD?
A
Hypersensitivity pneumonitis RA SLE Scleroderma Radiation therapy
5
Q
What drugs can cause ILD?
A
Amiodarone Methotrexate Nitrofurantoin Bleomycin Cyclophosphamide
6
Q
What are the clinical features of ILD?
A
Progressive breathlessness Dry cough for months Respiratory failure Cor pulmonale Clubbing Fine inspiratory crackles Cyanosis
7
Q
What is the gold standard investigation for ILD?
A
HRCT
8
Q
What other investigations are done in ILD?
A
Pulse oximetry ABGs Echocardiogram Immunological screen Serum ACE levels PFTs - restrictive
9
Q
What is shown on an HRCT in ILD?
A
Honeycombing
10
Q
When is a biopsy needed for diagnosis of ILD?
A
Young patient
Atypical clinical presentation
Atypical radiological features
Rule out malignancy
11
Q
What is shown on an x-ray in ILD?
A
Reticulo-nodular shadowing
12
Q
What is the treatment for ILD?
A
Removal from exposure Immunosuppressive therapy Antifibrotic drugs Treatment of co-morbidities Transplant O2 therapy Palliative care
13
Q
What are the complications of ILD?
A
Respiratory failure Pulmonary hypertension Acute exacerbation Respiratory infections ACS Thromboembolic disease Lung cancer
