Interleukins and Cytokines

Question 1

What interleukins/cytokines do macrophages produce?

Answer 1

IL-1, 6, 8, 12 and TNFalpha.

Question 2

What interleukins/cytokines do Th1 cells produce?

Answer 2

IL-2, 3 and IFNgamma.

Question 3

What interleukin do all activated Th cells produce?

Answer 3

IL-3

Question 4

What interleukin do Th2 cells produce?

Answer 4

IL-4, 5, 6 and 10.

Question 5

What interleukin do dendritic cells and B cells produce?

Answer 5

IL-12.

Question 6

What is the function of IL-1?

Answer 6

Acute inflammation, induced fever.

Question 7

What is the function of IL-2?

Answer 7

Stimulates growth and differentiation of T cell response.

Question 8

What is the function of IL-4?

Answer 8

Stimulates differentiation and proliferation of B cells.

Question 9

What is the function of IL-5?

Answer 9

Stimulates production of eosinophils.

Question 10

What is the function of IL-8?

Answer 10

Neutrophil chemotaxis.

Question 11

What is the function of IL-10?

Answer 11

Inhibits Th1 cytokine production (anti-inflammatory cytokine).

Question 12

What is the function of IL-12?

Answer 12

Activated NK cells and stimulates differentiation of naive T cells into Th1 cells.

Question 13

What is the function of TNFalpha?

Answer 13

Induces fever, neutrophil chemotaxis.

Question 14

What is the function of IFNgamma?

Answer 14

Activates macrophages.