Cardiovascular Treatment Pathways Flashcards
What are the 3 first line medications in CCF (with and without reduced ejection fraction)?
- Spironolactone in low ejection fraction heart failure, loop diuretics in preserved ejection fraction
- ACEIs or ARB.
- B-blockers (start low, go slow).
What drug would you add if CCF was not adequately controlled by first line medication?
Spironolactone.
When would you use digoxin in CCF?
If signs or symptoms of heart failure on standard therapy or have AF.
When would you use other vasodilators in CCF e.g. nitrates or hydralazine?
If patient intolerant to ACEIs or ARBS or are afro-Caribbean.
What drug would you use in CCF if HR is fast despite beta-blockers?
Ivabradine.
What are 3 other therapies for CCF?
ICDs, cardiac resynchronisation therapy (for prolonged QRS), transplant.
What is the treatment for right sided heart failure (cor pulmonale)?
Diuretics and oxygen.
What is the treatment for CCF caused by valvular disease?
Surgery.
What is the treatment for CCF caused by fast AF?
Digoxin or DC cardioversion.
What are the 5 steps in acute LVF therapy?
- Sit patient upright.
- High flow oxygen if hypoxic (care in COPD).
- IV furosemide.
- IV diamorphine.
- GTN if systolic BP greater than or equal to 90.
What is the acute treatment for a STEMI after taking an ECG?
M - morphine and anti-emetic. O - oxygen if hypoxic. N - nitrates (GTN spray) if BP >90mmHg. A - aspirin 300mg PO. \+ T - ticagrelor 180mg PO.
When would you do PCI and when would you do thrombolysis?
PCI if can be done within 120 mins of first medical contact, otherwise thrombolysis.
What are the major contraindications for thrombolysis?
Previous intracranial haemorrhage, ischaemic stroke (<6 months), cerebral malignancy or AVM (arteriovenous malformation), recent major trauma/surgery/head injury (<3 weeks), GI bleeding, known bleeding disorder, aortic dissection, non-compressible punctures.
What is the acute treatment for unstable angina or an NSTEMI?
Same treatment as STEMI (MONA+T).
What would you do to guide next steps in unstable angina or an NSTEMI?
Measure troponin and clinical parameters to assess risk e.g. GRACE score2.
What would a high risk patient with unstable angina or an NSTEMI have?
Rise in troponin, dynamic ECG changes or significant co-morbidities.
What would a low risk patient with unstable angina or an NSTEMI have?
No chest pain recurrence, no signs of heart failure, normal ECG, no troponin rise (repeat).
What would you do with a high risk patient with unstable angina or an NSTEMI?
Get a cardiologist review for angiography and PCI.
What times should angiography be done in unstable angina or an NSTEMI?
- <2 hours after presentation if ongoing angina or evolving ST changes, cardiogenic shock or life-threatening arrhythmias.
- <24 hours if high risk patient.
- <72 hours if low risk patient.
What would you do with a low risk patient with unstable angina or an NSTEMI?
Discharge, arrange further outpatient investigations e.g. stress test.