Cancer and Infection

Question 1

What type of cancers does the HPV cause?

Answer 1

Cervix, vulva, vagina, penis, anus, mouth or throat.

Question 2

What does E6 protein expressed by HPV do?

Answer 2

Destroys p53.

Question 3

What does E7 protein expressed by HPV do?

Answer 3

Prevents Rb from acting so allows E2F to promote transcription of DNA polymerase.

Question 4

What type of tumours does EBV cause?

Answer 4

Burkitt’s lymphoma, B-cell lymphomas, Hodgkin’s lymphomas, nasopharyngeal carcinomas.