Intergumentary System Flashcards
What is the integumentary system? What does it do?
Skin
Covers the entire surface of the body and is the largest organ of the body in terms of its weight and volume
Accessory structures of the skin
Hair, nails, and 3 types of glands (sebaceous, sweat, and apocrine)
Tissue types of the skin
Epithelium, CT, muscles, blood vessels, and nervous
6 functions of the skin
- Protection
- Prevention (of dehydration)
- Regulation (of body temp)
- Sensation
- Production of vitamin D
- Immunological
2 basic layers of the skin
Epidermis and dermis
Maximally keratinized stratified squamous epithelium
Epidermis
Cells that form the epidermis
Keratinocytes
Deepest layer of the epidermis, borders the dermis
Stratum basale
What type of cells lie on the basement membrane of stratum basale?
Single layer of cuboidal or tall cuboidal cells
How long does it take for the stem cells of the stratum basale to replace the epidermis?
3 to 4 weeks
What 3 special cells types are in the stratum basale?
- Keratinocyte stem cells
- Melanocytes
- Merkel cells/disks
Melanin producing cells found in the stratum basale
Melanocytes
Sensory receptor cells, which respond to continuous touch stimuli, found in the stratum basale
Merkel cells/disks
Layer of the epidermis that contains polyhedral keratinocytes, which become more flattened in the superficial part of this layer
Stratum spinosum
The plasma membrane of neighboring cells in the stratum spinosum is connected by..
Desmosomes (macula adherens)
Modified macrophages that are found in the stratum spinosum
Langerhans cells
Layer of the skin that contains flattened cells with kerato-hyalin granules in their cytoplasm
Stratum granulosum
Where is stratum granulosum more prominent?
In thick skin than thin skin
What basophilic cell type is found in the stratum granulosum?
Kerato-hyalin granules
Thin layer only found in thick skin
Stratum lucidum
Densely packed
Most superficial layer of the epidermis
Stratum corneum
The stratum corneum has cells that are completely filled with _________ and do not contain any ____________ or ___________.
Keratin
Nuclei or organelles
Therefore they’re dead. Constantly shed
CT layer just deep to the epidermis
Dermis
The dermis contains..
- Blood vessels
- Nerves
- Afferent sensory receptors
What types of afferent sensory receptors are found in the dermis?
Meissner corpuscles and free nerve endings
Transition/subcutaneous layer below the dermis of the skin
Hypodermis
Hypodermis contains…
- LCT
- Adipose tissue
- Nerves
- Arteries
- Veins