Basics of Embryology III Flashcards
Neurulation converts the neural plate into a hollow neural tube covered by: _______ __________
Surface ectoderm
The neural tube differentiates into
Brain and spinal cord
Even before the end of the 4th week, what major regions of the brain become apparent?
Forebrain Midbrain Hindbrain Mesencephalon Rhombencephalon
Where do neurons and glia begin to differentiate from (in the neural tube)?
Neuroepithelium
What cells detach from the lateral lips of the neural folds and migrate to numerous locations in the body for differentiation?
Neural crest cells
What is the fate os the neural crest cells from the hindbrain?
Pharyngeal arches of the head and neck.
Which later become the bones of the nose, face, middle ear, and neck
Neural crest cells from the mesencephalon and rhombencephalon form the..
Dermis
Smooth muscle
Fat of the face and ventral neck
Odontoblasts of the developing teeth
Neural crest cells from the caudalmost rhombencephalon become the..
Parafollicular cells of the thyroid
The rhombencephalic neural crest cells also contribute to some of the..
Cranial nerve ganglia
Aka neurons and all glial cells in the sensory ganglia of CN V, VII, IX and X
Which nerves does the rhombencephalic crest cells contribute to giving rise to?
5 7 9 and 10
Special sensory nerves, associated glia, and ganglia arise from what?
Placodes.
Wtf is a placode
What does CN1 arise from?
Olfactory placode
What does CN2 arise from?
Optic cup (distal end of which thickens as the placode-like rudiment of the neural retina)
what does CN7 arise from?
Optic placode.
Vestibulocochlear ganglion also arises from this
The entire cranial component of the parasympathetic division of the autonomic nervous system is formed from…
Cranial neural crest cells
What gives rise to the pita mater and arachnoid mater?
Cranial neural crest cells
What gives rise to the dura mater?
Head paraxial mesoderm
Cranial neural crest cells invade the surface ectoderm to form the…
Melanocytes of the skin of the head and neck
What are the 3 major contributions of neural cells from the vagal region?
- Outflow tract of the heart
- Enteric nervous system
- Parafollicular cells of the thyroid
The peripheral nervous system of the neck, trunk, and limbs includes the following four types of peripheral neurons:
- Peripheral sensory neurons
- The cell bodies of which they reside in the dorsal root ganglia
- Sympathetic and parasympathetic autonomic peripheral motoneurons
- The cell bodies of which reside, respectively, in the sympathetic and parasympathetic ganglia (and enteric neurons, considered a 3rd subdivision of the autonomic nervous system)
Shortly after somite formation, each somite reorganizes into two subdivisions:
- The epithelial dermamyotome
2. Mesenchymal sclerotome
Sclerotomes develop into the..
Vertebrae
Skins 2 layers
Epidermis and dermis
What is the epidermis formed by?
Surface ectoderm (mainly)
Also by neural crest cells (which form melanocytes)
Dermis is mostly..
Mesodermal
Face dermis is from neural crest cells
Where does development of bone and muscle occur?
Within mesenchymal regions of the embryo
What are the 2 ways of bone formation?
- Endochondral ossification
2. Intramembranous ossification
What is endochondral ossification?
A cartilage model first forms and is eventually replaced with bone
Formation of the axial skeleton, cranial base, and appendicular skeleton