Endocrine System Flashcards
Ductless gland whose secretion is released directly into the bloodstream
Endocrine gland
Glands making up the endocrine system
Pituitary, thyroid, parathyroid, adrenal, pineal
Other organs that secrete hormones but are not part of the endocrine system
Hypothalamus Thymus Pancreas Ovaries Testes Kidneys Stomach Liver Small intestine Skin Heart Adipose tissue
Define exocrine gland
Gland whose secretion is drained by ducts onto the body surface OR into a body cavity
DUCTED GLANDS
Examples of exocrine glands
Sebaceous
Sudiferous
Mammary
Define hormone
Substances produced in one part of the body and transported to another where they affect chemical actions or the secretion of other hormones
The body’s method of maintaining its internal environment within certain physiological limits
Homeostasis
Hormones affect only specific cells called
Target cells
Hormones that enter the bloodstream to reach distant target cells are called
Circulating hormones
Circulating hormones may remain in the blood for how long? And when will they stop?
Few minutes to few hours
When the liver inactivates it and kidneys excrete it
Hormones that do not enter the bloodstream to reach target cells are called
Local hormones
Paracrine
Local hormone acting on neighboring cells (histamine)
Autocrine
Local hormone acting on the same cell that secreted it (interleukin-2)
How are local hormones inactivated?
By enzymes in the interstitial fluid which surrounds cells
3 different hormone interactions
Permissive effect (one hormone enhances the effect of another hormone)
Synergistic effect (2 hormones working together are better than 1)
Antagonistic effect (1 hormone has a greater effect than another)
The synthesis and release of most hormones are through a. ___________________________, which is a corrective mechanism that helps maintain homeostasis
Negative feedback system
What stimulates or inhibits hormonal secretions?
Humoral stimuli (changing levels of ions and nutrients in the blood)
Hormonal stimuli (release of other hormones)
Neural stimuli (nervous system)
The “master” endocrine gland
Pituitary gland/hypophysis
Major link bringing together the nervous and endocrine systems
Hypothalamus
What does the hypothalamus synthesize?
Oxytocin and ADH
Together, the hypophysis and hypothalamus regulate what?
Practically all aspects of growth, development, metabolism, and homeostasis
Location of the hypothalamus
Inferior to the two lobes of the thalamus
Location of the hypophysis
Sits in the sella turcica of the sphenoid bone. Located inferiorly to the hypothalamus