Endocrine System Flashcards

1
Q

Ductless gland whose secretion is released directly into the bloodstream

A

Endocrine gland

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2
Q

Glands making up the endocrine system

A

Pituitary, thyroid, parathyroid, adrenal, pineal

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3
Q

Other organs that secrete hormones but are not part of the endocrine system

A
Hypothalamus
Thymus
Pancreas
Ovaries
Testes
Kidneys
Stomach
Liver
Small intestine
Skin
Heart
Adipose tissue
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4
Q

Define exocrine gland

A

Gland whose secretion is drained by ducts onto the body surface OR into a body cavity

DUCTED GLANDS

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5
Q

Examples of exocrine glands

A

Sebaceous
Sudiferous
Mammary

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6
Q

Define hormone

A

Substances produced in one part of the body and transported to another where they affect chemical actions or the secretion of other hormones

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7
Q

The body’s method of maintaining its internal environment within certain physiological limits

A

Homeostasis

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8
Q

Hormones affect only specific cells called

A

Target cells

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9
Q

Hormones that enter the bloodstream to reach distant target cells are called

A

Circulating hormones

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10
Q

Circulating hormones may remain in the blood for how long? And when will they stop?

A

Few minutes to few hours

When the liver inactivates it and kidneys excrete it

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11
Q

Hormones that do not enter the bloodstream to reach target cells are called

A

Local hormones

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12
Q

Paracrine

A

Local hormone acting on neighboring cells (histamine)

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13
Q

Autocrine

A

Local hormone acting on the same cell that secreted it (interleukin-2)

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14
Q

How are local hormones inactivated?

A

By enzymes in the interstitial fluid which surrounds cells

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15
Q

3 different hormone interactions

A

Permissive effect (one hormone enhances the effect of another hormone)

Synergistic effect (2 hormones working together are better than 1)

Antagonistic effect (1 hormone has a greater effect than another)

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16
Q

The synthesis and release of most hormones are through a. ___________________________, which is a corrective mechanism that helps maintain homeostasis

A

Negative feedback system

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17
Q

What stimulates or inhibits hormonal secretions?

A

Humoral stimuli (changing levels of ions and nutrients in the blood)

Hormonal stimuli (release of other hormones)

Neural stimuli (nervous system)

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18
Q

The “master” endocrine gland

A

Pituitary gland/hypophysis

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19
Q

Major link bringing together the nervous and endocrine systems

A

Hypothalamus

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20
Q

What does the hypothalamus synthesize?

A

Oxytocin and ADH

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21
Q

Together, the hypophysis and hypothalamus regulate what?

A

Practically all aspects of growth, development, metabolism, and homeostasis

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22
Q

Location of the hypothalamus

A

Inferior to the two lobes of the thalamus

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23
Q

Location of the hypophysis

A

Sits in the sella turcica of the sphenoid bone. Located inferiorly to the hypothalamus

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24
Q

What attaches the pituitary gland to the hypothalamus?

A

Infundibulum

25
What are the two lobes of the pituitary gland?
Anterior lobe (adenohypophysis) Posterior lobe (neurohypophysis)
26
What stimulates the synthesis and release of hormones from the anterior lobe? Suppresses?
Releasing hormones (RHs) Inhibiting Hormones (IHs)
27
There are _ different types of cells in the Anterior lobe that secretes _ major hormones.
5 7
28
What secretes HGH?
Somatotrophs (of the anterior lobe of hypophysis)
29
What secretes TSH?
Thyrotrophs, of the anterior lobe of hypophysis
30
What produces FSH and LH?
Gonadotrophs of the anterior lobe of hypophysis
31
What produces prolactin?
Lactotrophs of AL of PG
32
What secretes adrenocoritotropic hormone (ACTH) and melanocytes-stimulating hormone (MDH)?
Corticotrophs of AL of PG
33
The PL of PG stores and releases what 2 hormones?
Oxytocin and ADH Synthesized by neurosecretory cells in the hypothalamus
34
Location of the thyroid gland
Right and left lobes lie on either side of the trachea Isthmus lies anterior to the trachea
35
Thyroid gland consists of __________ ____________ The wall of each of these structures consists of what 2 types of cells?
Thyroid follicles Follicular cells and parafollicular cells
36
What secretes T3 and T4?
Follicular cells of the thyroid gland
37
What secretes calcitonin?
Parafollicular cells of the thyroid gland
38
Most important function of the thyroid hormones/gland
To increase basal metabolic rate (to maintain body temp)
39
Where are the parathyroid glands?
On the posterior side of the thyroid gland.
40
Parathyroid glands consists of what 2 cell types?
Principal/chief cells and oxyphil cells (function unknown)
41
What secretes PTH?
Principal/chief cells of the PTG
42
Location of the Adrenal/suprarenal glands
Paired, on each kidney
43
Each adrenal gland has a covering _________ of CT, then the adrenal ________, and an innermost adrenal _________
Capsule Cortex Medulla
44
3 zones of the adrenal cortex
Zona glomerulosa (controls water and electrolyte) Zona fasciculata (increase fat and protein breakdown) Zona reticularis (cells produce male sexual hormone)
45
Adrenal medulla contains what type of cells? What do they secrete?
Chromatin cells The fight or flight hormones, Epinephrine/Adrenaline and Norepinephrine/Noradrenaline
46
Location of the pineal gland
Inferior to the posterior portion of the brains corpus callosum
47
The pineal gland contains secretory cells called ____________ which form the hormone ___________
Pinealocytes Melatonin
48
Melatonin is important to JEREMY BECAUSE WHY
Its an antioxidant protecting the CNS and maintains CIRCADIAN RHYTHM JEREMY YOU NEED MELATONIN DUDE
49
Functions of the pancreas (2 portions)
Exocrine portion (produces digestive enzymes) Endocrine portion (produce hormones to raise and lower blood glucose)
50
What makes of 99% of the pancreatic cells?
The exocrine portion (digestive enzymes)
51
Clusters of exocrine cells that produce digestive enzymes in pancreas
Acini
52
In the acini, there's 1-2 million tiny clusters of endocrine tissues called:
Islets of langerhans
53
Each islet of langerhans contains 4 cells types:
A-cells B-cells D-cells F-cells
54
What produces glucagon?
alpha cells of pancreas
55
What produces the insulin?
Beta cells of pancreas
56
Function of glucagon
Raise blood glucose level
57
Function of insulin
Lowers blood glucose levels
58
Function of the ovaries
Produce the ovum | Produce sex hormones (estrogen and progesterone)