INTERFERING FACTOR ON MOST HEMATOLOGY ANALYZERS

Question 1

WBC over 50, 000/uL

Parameter Affected
1. false increase in ____
- solution
2. false increases in ___
- solution
3. is also affected because it is calculated using the affected factors above

Answer 1

1. RBC COUNT
   - DILUTE SAMPLE (increase)
2. HEMOGLOBIN
   - perform spun hematocrit
3. HEMATOCRIT

Question 2

NUCLEATED RBC
Parameter Affected
1. increase in ____
- solution

DIRT
Parameter Affected
1. increase in ____
- solution

Answer 2

NUCLEATED RBC
Parameter Affected
1. increase in WBC count
- use the formula for corrected wbc

DIRT
Parameter Affected
1. increase in cell count
- clean before use

Question 3

Cold agglutinins

Parameter Affected
1.
- increase in ____
- decrease in ____
2. solution

Answer 3

Parameter Affected
1.
- increase in MCV
- decrease in RBC count
2. Prewarm the blood

Question 4

Platelet threshold is ___ only

1. Giant Platelets: decrease in __
2. Platelet clumps: increase in ____
   - this is due to 50fL size of platelets, which will fall under red cells
3. Satellitism: decrease in ____
4. Solution:
   - examine ____
   - if present, recollect in _____ diluted in ratio of __:__

Answer 4

2-20fL

1. decrease in platelets
2. increase in rbc count
3. decrease in platelets
4. Solution:
   - blood film
   - sodium citrate; 1:1

Question 5

LIPEMIA
1. increase __, __, ___
- solution

HEMOLYSIS
1. decrease in __ & ___
2. increase in __ & ___
3. solution
- in vitro:
- in vivo:

Answer 5

LIPEMIA
1. increase HB, MCH, MCHC
- FOLLOW MANUFACTURERS INSTRUCTIONS

HEMOLYSIS
1. RBC & HCT
2. MCH & MCHC
3. solution
- RECOLLECT
- NO REMEDY; JUST PERFORM HB MANUALLY

Question 6

OLD SPECIMEN
1. increase
2. decrease
3. solution

SCHISTOCYTES
1. increase
2. decrease
3. solution

Answer 6

OLD SPECIMEN
1. MCV
2. PLT
3. RECOLLECT

SCHISTOCYTES
1. PLT
2. RBC
3. MANUAL COUNT/SPUN HCT METHOD

Question 7

RESISTANT RBC
1. increase
2. decrease
3. solution

FRAGILE WBC (CHEMOTHERAPY)
1. increase
2. decrease
3. solution

Answer 7

RESISTANT RBC
1. WBC
2. HGB
3. MANUAL HGB OR ADD DISTILLED WTER TO LYSE RBC

FRAGILE WBC
1. PLT
2. WBC
3. MANUAL COUNT