Integumentary System Flashcards
Composition
Body membrane (epithelial & connective membrane)
Skin appendages
(Hair, nails, sweat and oil glands)
Functions
- protect, insulate, cushion the body organs
- protect against mechanical, chemical, thermal, UV damage, and bacteria
- regulate heat loss by the NS
- Vit D synthesis
Structure
(Cutaneous membrane)
- epidermis (stratified squamous epithelium)
- dermis (dense connective tissue)
- (hypodermis (adipose tissue))
Homeostatic imbalance
Cancer
- highest factor: UV radiation
- either benign or malignant
Epidermis
Avascular
-five layers (strata)
-mostly keratinocytes
-stratum basale (base): active division of daughter cells
-stratum spinosum, granulosum: cells become flatter and keratinize. Cells die after stratum granulosum
-stratum lucidium: (clear layer, only on hairless areas)
-stratum corneum: (3/4 of epidermis thickness)
Protects body from blood loss, physical, chemical damage
Melanin
- pigment produced by melanocytes
- mostly in stratum basale
- colour goes from yellow to brown to black
- melanosomes: melanin accumulated membrane-bound granules
- amount produced dependent on genetics and exposure to sunlight
Epidermal dendritic cells
-alert and activate immune cells to a threat (bacterial or viral invasion)
Merkel cells
- Associated with sensory nerve endings
- at the junction of the epidermis-dermis
- serve as touch receptors (Merkel discs)
Dermis
Two layers: papillary (upper dermal region) and reticular
Papillary layer of dermis
- superficial layer of areolar Tissue
- uneven, peg-like projection indenting epidermis (dermal papillae)
- many projections contain capillary loops, and others house pain and touch receptors
- on hairless surface, there is increased friction and gripping ability
- fingerprints are identifying films of sweat
Reticular layer of the dermis
- deep layer of dense connective Tissue
- contains blood vessels, sweat and oil glands
- deep pressure receptors: lamellar corpuscules