Integumentary system Flashcards
what is the largest organ of the body in terms of weight and volume?
skin, dumbass
what are the three types of glands
- sebaceous
- eccrine sweat
- apocrine
what are the six functions of skin?
- protection from pathogens and UV light
- Prevention of dehydration
- Regulation of body temperature
- Sensation
- Immunological function of Langerhan cells
- Production of Vitamin D
what kind of epithelium is the epidermis?
maximally keratinized stratified squamous
the epidermis has five layers of what kind of cells?
Keratinocytes
what is the deepest layer of the epidermis?
Stratum Basale
what kind of cells make up the stratum basale?
-cuboidal or tall cuboidal cells
how many weeks does it take for kerotinocytes to finish their renewal cycle?
3-4 weeks
what are the two special types of cells, besides kerotinocytes, that are found in the stratum basale?
- melanocytes
- merkel cells
what do melanocytes produce?
melanin granules
-insert them into keratinocytes
what kind of cells are merkel cells?
- sensory receptor cells
- respond to CONTINUOUS TOUCH stimuli
what is the waterproof barrier layer of the epidermis?
Stratum spinosum
what kind of cells are in the stratum spinosum?
- polyhedral keratinocytes
- Langerhan cells
what are langerhan cells?
modified macrophages
plasma membrane of neighboring cells in the stratum spinosum are connected by what?
-desmosomes
what kind of cells are located in the stratum granulosum?
Keratinocytes
-flattened cells with Kerato-hyalin granules in their cytoplasm
is the stratum granulosum more prominent in thick or thin skin?
thick
what happens when cells are maximally keratinized?
death
what kind of skin is stratum lucidum found in?
thick skin only!
Tell me about the stratum lucidum
- tightly condensed cells that lie beneath the stratum corneum
- cells in the process of dying
- once nucleus shrivels up, they become stratum corneum
what is the most superficial layer of epidermis?
stratum corneum