Integumentary System Flashcards

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1
Q

the skin is composed of two distinct layers ..

A

The epidermis
The dermis

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2
Q

The epidermis

A

composed of epithelial cells, is the outermost protective shield of the body.

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3
Q

The underlying dermis ..

A

making up the bulk of the skin, is a tough, leathery layer composed mostly of dense connective tissue.

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4
Q

The vascularized layer is and how ? ..

A

Dermis. Nutrients reach the epidermis by diffusing through the tissue fluid from blood vessels in the dermis.

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5
Q

The subcutaneous tissue ..

A

the hypodermis, deep to the skin & is not part of the skin, but it shares some of the skin’s protective functions.

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6
Q

The hypodermis, also called ..

A

superficial fascia because it is superficial to the tough connective tissue wrapping (fascia) of the skeletal muscles, consists mostly of adipose tissue.

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7
Q

the hypodermis function ..

A

anchors the skin to the underlying structures (mostly to muscles), but loosely enough that the skin can slide relatively freely over those structures.

acts as a shock absorber and an insulator that reduces heat loss.

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8
Q

The epidermis consists of ————— cell types and ———— layers.

A

four distinct, four or five distinct.

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9
Q

The cells populating the epidermis include ..

A

keratinocytes, melanocytes, dendritic cells, and tactile cells.

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10
Q

The chief role of keratinocytes is ..

A

to produce keratin, the fibrous protein that helps give the epidermis its protective properties.

Most epidermal cells are keratinocytes

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11
Q

keratinocytes arise in the deepest part of the epidermis from a cell layer called ..

A

stratum basale.

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12
Q

keratinocytes undergo almost continuous mitosis in response to prompting by ..

A

epidermal growth factor

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13
Q

epidermal growth factor ..

A

peptide produced by various cells throughout the body.

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14
Q

callus

A

thickening of the epidermis

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15
Q

Melanocytes

A

spider-shaped epithelial cells that synthesize the pigment melanin are found in the deepest layer of the epidermis.

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16
Q

As melanin is made, it accumulates in ..

A

membrane-bound granules called melanosomes that motor proteins move along actin filaments to the ends of the melanocyte’s processes

17
Q

From melanocyte’s processes melanosomes are transferred to a number of nearby keratinocytes. The melanin granules accumulate on the ..

A

superficial side of the keratinocyte nucleus, forming a shield that protects the nucleus from the damaging effects of (UV).

18
Q

dendritic cells

A

Also called Langerhans cells, star-shaped, they arise from bone marrow and migrate to the epidermis.

19
Q

Dendritic Cells function ..

A

ingest foreign substances and are key activators of our immune system.

20
Q

tactile cells

A

Also called merkel cells, present at the epidermal-dermal junction.
Shaped like a spiky hemisphere

21
Q

tactile (Merkel) cells function..

A

each tactile cell is intimately associated with a disclike sensory nerve ending. The combination, called a tactile or Merkel disc, functions as a sensory receptor for touch

22
Q

The stratum basale

A

the deepest epidermal layer, is attached to the underlying dermis

23
Q

stratum basale consists of ..

A

a single row of stem cells—a continually renewing cell population—representing the youngest keratinocytes.

24
Q

What is the alternate name of stratum basale, and why ?

A

stratum germinativum, The many mitotic nuclei seen in this layer reflect the rapid division of these cells.

25
Q

The stratum spinosum

A

Also called Prickly Layer, several cell layers thick. These cells contain a weblike system of intermediate filaments.

26
Q

The weblike system of intermediate filaments in Prickly Layer function is ..

A

tension-resisting bundles of pre-keratin fila- ments, which span their cytosol to attach to desmosomes.

27
Q

the keratinocytes in stratum spinosum layer appear to have ..

A

spines, causing them to be called prickle cells