Integument Physiology II Flashcards
Thickness of skin layers (from thickest to thinnest).
Hypodermis, dermis, epidermis
Pneumonic for layers of epidermis?
Come Get Sun Burnt
List four layers of epidermis? Innermost to outermost?
Stratum basale, stratum spinosum, stratum granulosum, stratum corneum
How many layers in stratum basale? Types of cells? Most common type of cell? Movement?
Single layer; columnar to cubiodal cells; keratinocytes; upwards to replenish epidermis
Main functions of stratum basale?
- Anchor epidermis to dermis
- Proliferative and reparative (stem cell function)
What is another name for the stratum spinosum?
Prickle cell layer
Composition of SS?
Daughter cells of SB
How many layers in SS?
1-2 layers thick
Why is the SS also called prickle cell layer?
keratinocytes are also connected by intercellular bridges or prickles
What does the stratum spinosum synthesize?
lamellar granules (glycoproteins, glycolipids, phospholipids)
Function of lamellar granules?
barrier function
Composition of SG?
SS and SS daughter cells
Three substances in SG?
Pilofilaggrin, keratin filaments, loricin
SG thickness in haired vs non haired regions?
1-2 cells thick; 4-8 cells thick
Cell shape and color of SG?
Flattened and basophilic (blue)
What are filaggrin degradation products responsible for?
SC hydration and UV light barrier