Integrated Approach to Psychopathology Flashcards
Relative number of genes that influence mental illness
Mental illness is polygenetic
Genetic contribution to mental illness
<50%
Diathesis-stress model
Diathesis: genetic vulnerability
Stress: life events
Diathesis + stress = disorder
Reciprocal gene-environment model
Genes impact environment
Environment impacts genes
Action potential
Electrical charge that travels down the neuron and triggers release of neurotransmitters
Synaptic transmission
- Neuron A releases neurotransmitters into synapse
- Neurotransmitters bind with receptors on neuron B
- Enough neurotransmitters bind with receptors, neuron B fires
- Extra neurotransmitters in synapse are removed (breakdown and reuptake)
Neurotransmitters
Allow for neural communication
Hundreds in human body, but 6 extensively studied
Function depends on location in brain
Serotonin (5-HT)
Neurotransmitter
Mood, sleep, learning
Norepinephrine
Neurotransmitter
Mood, arousal
Dopamine
Neurotransmitter
Movement, pleasure
Acetylcholine (ACH)
Neurotransmitter Muscles (contraction and restriction) Botox disrupts; black widow venom increases
Gamma aminobutyric acid (GABA)
Neurotransmitter
Slows down brain
Used in anti-anxiety drugs
Glutamate
Neurotransmitter
Stimulates brain
Agonists
Increases production and availability of neurotransmitters
Antagonists
Decreases availability of neurotransmitters
Medulla
Hindbrain
Life sustaining processes
Pons
Hindbrain
Regulation of sleep stages