Integrated Approach to Psychopathology Flashcards
Relative number of genes that influence mental illness
Mental illness is polygenetic
Genetic contribution to mental illness
<50%
Diathesis-stress model
Diathesis: genetic vulnerability
Stress: life events
Diathesis + stress = disorder
Reciprocal gene-environment model
Genes impact environment
Environment impacts genes
Action potential
Electrical charge that travels down the neuron and triggers release of neurotransmitters
Synaptic transmission
- Neuron A releases neurotransmitters into synapse
- Neurotransmitters bind with receptors on neuron B
- Enough neurotransmitters bind with receptors, neuron B fires
- Extra neurotransmitters in synapse are removed (breakdown and reuptake)
Neurotransmitters
Allow for neural communication
Hundreds in human body, but 6 extensively studied
Function depends on location in brain
Serotonin (5-HT)
Neurotransmitter
Mood, sleep, learning
Norepinephrine
Neurotransmitter
Mood, arousal
Dopamine
Neurotransmitter
Movement, pleasure
Acetylcholine (ACH)
Neurotransmitter Muscles (contraction and restriction) Botox disrupts; black widow venom increases
Gamma aminobutyric acid (GABA)
Neurotransmitter
Slows down brain
Used in anti-anxiety drugs
Glutamate
Neurotransmitter
Stimulates brain
Agonists
Increases production and availability of neurotransmitters
Antagonists
Decreases availability of neurotransmitters
Medulla
Hindbrain
Life sustaining processes
Pons
Hindbrain
Regulation of sleep stages
Cerebellum
Hindbrain
Fine motor coordination
Hypothalamus
Limbic system
Basic drives (hunger, thirst, sex drive, etc.)
Organizes pituitary gland, which releases hormones
Amygdala
Limbic system
Emotions (anger, fear)
Hippocampus
Limbic system
Consolidation of memory (gateway by which new memories are made; doesn’t store memories)
Frontal lobe
Cerebral cortex
Thinking, movement, executive function, emotional regulation
Motor cortex: different areas trigger different parts of body to move
Parietal lobe
Cerebral cortex
Touch
Primary somatosensory cortex: different areas process touch info from different parts of body
Occipital lobe
Cerebral cortex
Visual integration