insomnia (1)

Question 1

how often do you have to have “sleep disturbances” to be classified as insomnia?

Answer 1

at least 3 nights per week and persists for at least 3 months

Question 2

what is most common cause of insomnia?

Answer 2

caffiene

Question 3

what are the 4 neurotransmitters than can be in excess in insomnia and where do they come from

Answer 3

1. norepi from locus ceruleus
2. serotonin from the raphe nucleus
3. dopamine from the ventral tegmental area
4. histimine from the tuberomamillary nucleus

Question 4

what 3 neurotransmitters can be deficient at night in insomnia?

Answer 4

GABA
melatonergic tone
adenosinergic tone

Question 5

list some examples of behaivoral therapy for insomnia

Answer 5

diary/log book, progressive relaxation, self hyponosis

Question 6

what are 2 OTC meds that can help insomnia?

Answer 6

antihistamines & melatonin

Question 7

what are 3 prescription agents that are non habbit forming

Answer 7

• antihistamines doxepin

- melatonin 1+2 agonists: ramelteon, tasimelteon

Question 8

what are 4 prescription agents that are mildly habit forming?

Answer 8

• benzodiazepine receptor agnosts: zolpidem, zaleplon, ezopiclone
• orexin 1+2 antagonists: suvorexant

Question 9

what are 5 prescription agents that are habit forming

Answer 9

• benzodiazepines: triazolams, temaxepam, fluazepam
• trazodone (sedating antidepressant)
• quetiapine (sedating antipsychotic)