Dementia

Question 1

What are the triad of symptoms a patient must have to be considered to have alzheimers?

Answer 1

functional, behavioral, cognitive

Question 2

What’s the one cause of dementia that cholinesterase inhibitors are not indicated for?

Answer 2

Pick’s disease

Question 3

What are the treatment options for pick’s disease?

Answer 3

atypical antipsychs
divalproex - behavioral control
SSRIs - irritability and depression

Question 4

What are the four cholinesterase inhibitors?

Answer 4

1. tacrine
2. donezepil
3. rivastigmine
4. galantamine

Question 5

Which of the cholinesterase inhibitors are metabolized by Cyt P450s?

Answer 5

tacrine, donezepil, galantamine

Question 6

How is rivastigmine metabolized?

Answer 6

cholinesterase

Question 7

Which cholinesterase inhibitors produce hallucinations and leads to sleep disturbance?

Answer 7

donezepil

Question 8

What drug is a NMDA antagonist and is used in conjunction with cholinesterase inhibitors?

Answer 8

Memantine

Question 9

In picks disease or alzheimers do the tau NFTs form in the shape of the neuron?

Answer 9

alzheimers