Innate immunity Flashcards

1
Q

innate immunity

A

is the first line of defence, and responds to a broad range of microbes

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2
Q

traits of innate immunity

A
  • rapid
  • no memory is formed
  • response is not stronger after being exposed
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3
Q

external innate imunity

A
  • epithelia acts as a physical, chemical barrier with intraepithelial lymphocytes, and has flora. there is also the mucciliary part, and flushing out done by saliva, urine, tears
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4
Q

what is the blood differential test

A

it measures the percentage of each type of white blood cell you have in blood.

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5
Q

what are normal blood test results

A

neutrophils: 60-70%
lymphocytes: 20-30%
monocytes: 2-8%
esoinophils: 2-4%
basophils: 1%

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6
Q

function of monocytes

A

phagocytosis, inflammation, T cell activation, tissue repair

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7
Q

neutrophils

A

phagocytosis, inflammation

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8
Q

NK cells

A

killing infected or tumor cells

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9
Q

dendritic cells

A

phagocytosis, activation of naive T cells

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10
Q

mast cells

A

inflammation

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11
Q

esoinophils

A

defence against parasites

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12
Q

what is the role of phagocytes in innate immunity

A
  • entry of pathogen
  • recognition of pathogen
  • phagocytosis and killing of pathogen
  • induction of inflammation
  • attraction of cells to infection site
  • pathogen elimination or adaptive immunity activation
  • tissue repair and remodling
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