Inheritence Flashcards

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1
Q

In the result of self-fertilization of dihybride cross the ratio of seeds which contain both dominant characters is

A

9/16
RrYy × RrYy
=> Cross them by using punet’s square
Then:
=> Phenotype: 9 : 3 : 3 : 1
9 = Round Yellow
3 = Round green
3 = Wrinkle yellow
1 = Wrinkle green

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2
Q

The distance between gene A and B is 9 centiMorgan and B and C is 9.5 the actual distance between A and C will be

A

9+9.5 = 18.5% = actual distance
=> 17% Recombinant frequency

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3
Q

The property due to which offspring show similarities with their parents is called

A

heredity
=> Characters transfer from parent called inheritance.
=> If phenotype of parental same as in offspring, then it is called hereditary.
genetics is variation and heredity

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4
Q

If phenotype is O because of recessive H gene the possible I gene may be

A

any of them
Hh, HH => h substance present so antigen present
hh => h substance absent so antigen is absent
=> If H substance is missing it masks the effect of the (I gene) and genotype will be A, B, AB but phenotype will be O Blood group.

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5
Q

Blood group O is universal donor because of

A

antigen
=> Donor depends on Antigen
=> Recipient depends on antibody
↳ Both for blood transfuse
no antigen ← O -ive = universal donor
AB +ive = universal acceptor

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6
Q

During determination of gene linkage the ratio of recombinant is similar to parental , the genes are

A

{Parental = Recombinant} → No linkage
{All parental} → complete linkage
{More parental, Less recombinant} → incomplete linkage

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7
Q

Interaction between alleles of different genes is called

A

non allelic and epistasis
both are intergenic interactions

Epistasis occurs when two or more different gene loci contribute to the same phenotype, but not additively. Epistasis is often described as occurring when one gene locus masks or modifies the phenotype of a second gene locus. The epistatic gene pair is present on non-homologous chromosomes, an interaction that is termed as non-allelic.

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8
Q

XXY in drosophila represent

A

fertile female
Male ← XXY = Kline filter syndrome in human
Female ← XXY = in drosophila fertile
Female

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9
Q

In a dominant relation the interaction is

A

inter allelic
=> According to Mendelian inheritance there is inter allelic interaction
=> Non Mandelian inheritance have intergenic interaction (interaction b/w alleles of different genes)

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10
Q

The genotypic ratio of F2 generation in monohybrid cross is

A

1:2:1
Genotype in F2:
RR Rr rr
1 : 2 : 1
Phenotype in F2
3 : 1

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11
Q

Number of linkage groups in drosophila are

A

4
No of linkage groups in an organism are equal to number of homologous pair of chromosomes.
⟹ Drosophila has 4 homologous pair of chromosomes so 4 linkage groups.
Linkage groups
Linkage group refers to a group of genes which are present in one chromosome. In other words, all those genes which are located in one.
Chromosome constitute one linkage group. The number of linkage groups is limited in each individual. The maximum number of linkage groups is equal to the haploid chromosome number of an organism.
For example: There are ten linkage groups in corn (2n = 20), seven in garden pea (2n = 14), seven in barley (2n = 14), four in Drosophila melanogaster (2n = 8) and 23 in man (2n = 46).

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12
Q

what were the characteristics studied by mendel
in a pea plant

A

Following seven characteristics were studied by Mendel:
1) Flower color 2) Flower position
3) Seed shape 4) Seed color
5) Pod shape 6) Pod color
7) Stem height
conducted exp on 29,000 pea plants

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13
Q

The contrasting pair of a factor in Mendelian crosses are called:

A

alleles
The contrasting pairs of factors in Mendelian crosses are called allelomorphs or Alleles.

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14
Q

Y-linked, or holandric genes include the gene that initiates

A

differentiation of the embryo into a male, several genes that encode testis specific spermatogenesis factors, a minor histocompatibility antigen (termed HY), and a gene in which mutations can cause hearing loss (DFNY1).
♦ Y-linked or holandric inheritance implies that only males are affected.
♦ Male-to-male transmission. An affected male transmits Y-linked traits to all of his sons but to none of his daughters.

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15
Q

According to modern concept, Mendel’s factor is called as ________.

A

genes

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16
Q

Mendel’s law of segregation is also known as _________________

A

Law of purity of gametes
When a pair of alleles is brought together in a hybrid (F1) they remain together without contaminating each other and they separate or segregate from each other into a gamete during the formation of gametes

17
Q

Which law states that the inheritance of one trait is independent on the inheritance of another trait?

A

Law of independent assortment
the allele a gamete receives for one gene does not influence the allele received for another gene.
According to the law of dominance, a trait is represented by two contrasting factors of a gene in a heterozygous individual; the allele/factor that can express itself in a heterozygous individual is called as a dominant trait. Whereas the law of segregation states that the two factors for a trait, present together in a heterozygous individual, do not get mixed and are separated during gametogenesis.
ratio is 9:3:3:1
◉ Using a dihybrid cross, Mendel developed the law of independent assortment.
◉ The law of independent assortment states that each pair of alleles segregates independently of each other pair of alleles during gamete formation.
◉ Strictly speaking, this law applies only to genes on different, nonhomologous chromosomes.
◉ Genes located near each other on the same chromosome tend to be inherited together.

18
Q

Which of the following crosses and ratio best demonstrates the law of segregation?

A

Aa×Aa
3:1
applies to non homologus chromosomes

19
Q

The Mendelian principle which has always stood true is

A

The law of segregation
n these principles, the law of dominance and Law of Independent assortment have deviations or exceptions. Law of segregation does not have any deviations of exceptions. So it always stands true.
Law of segregation is the universally accepted law of inheritance. It is the only law without any exceptions. It states that each trait consists of two alleles which segregate during the formation of gametes and one allele from each parent combines during fertilization, both parents contribute to the factors of offspring equally. In case, alleles of a pair are heterozygous, one is dominant and other recessive, alleles are not mixed up, the dominant one gets expressed. The recessive traits tend to reappear in the subsequent generation.
There is no such contrary model indicating that alleles mix up in the progeny so far, hence it is accepted and applicable

20
Q

Occasionally, a single gene may express more than one trait or effect. The phenomenon is called

A

This phenomenon is called pleiotropy, Polygeny refers to a single characteristic that is controlled by more than two genes

21
Q

ABO blood grouping in human is an example of

A

co dominance and multiple allelism

22
Q

Mendelian recombination’s are due to

A

Independent assortment of characters

23
Q

All genes located on the same chromosome

A

Form one linkage group

24
Q

Mendel’s perform series of experiments on pea plant because it’s _________?

A

Flowers were hermaphrodite
Had sharply distinct trait
Self-fertilization is easy

25
Q

sex determination for bees

A

N - male
NN - female
both are homogametic

26
Q

sex determination for chicken

A

ZZ - male
ZO- female

27
Q

Mendel used________________ for his experiment

A

Pisum sativum
garden pea

28
Q

describe heamophilla C

A

less than 1 percent
autosomal linakge on chromosome 19
equal chances in both sex

29
Q

Mendel was not imagining about which of the following?

A

Linkage
inkage of genes phenomenon was discovered by Bateson and Punnet (1906) in Lathyrus odoratus.

30
Q

Phenotype of an organism is the result of

A

Genotype and environment interactions

31
Q

what is the limit of crossing over frequency

A

it can’t exceed 50 perecnt

wow

32
Q

The mechanism that causes a gene to move from one linkage group to another is called

A

Translocation

Human have 22 autosomal linkage groups, one X and one Y linkage group. Rearrangement of chromosomal segment between two non-homologous chromosomes i.e., translocation moves gene of one linkage group to that of other, which occurs due to an induced abnormality and is not part of the regular cell cycle.
Inversion and duplication cause rearrangement of genes on same chromosome. There is a change in the order of genes within the same linkage group.
Crossing over results in exchange of genes between two homologous chromosomes. A process that occurs during Meiosis I resulting in recombination.

33
Q

Which one of the following trait undergo a zigzag pattern from maternal Grand-father to a Grand-son?

A

X-linked.
X-linked recessive trait follow a zigzag pattern. Son inherits X chromosome only from his mother and daughter gets X chromosome from each parent. So the X linked trait passes on from maternal grandparent to grand son through the daughter.

34
Q

In Drosophila sex is determined by

A

Ratio of number of X-chromosomes to the sets of autosomes

♦ Sex in Drosophila is determined by Genic Balance Mechanism.
♦ Ratio of X chromosomes: haploid sets of autosomes (X: A)
♦ X chromosome = Female producing effects
♦ Autosomes = Male producing effects
♦ Y Chromosome = Fertility factor in male
♦ X:A ratio
Female = 1.0 (2X:2n)
Male = 0.5 (1X:2n)
0.6 < X:A < 1.0 = intersex

35
Q

During his experiment, Mendel called the genes by the term

A

Elementen

36
Q

Hemophilia B is due to absence or abnormality of blood clotting factor:

A

IX

is 20%
A is caused by blood failing to clot agter injury