INHERITED DISORDERS OF COAGULATION

Question 1

Hemophilias is AKA?

Answer 1

Love hemorrhage

Question 2

Hemophilias are characterized by a deficiency of the?

Answer 2

Antihemophilic factors

Question 3

Enumerate the inherited disorders of coagulation

Answer 3

Hemophilia A
Hemophilia B
Hemophilia C
Prekallikrein; HMWK; FACTOR XII DEFICIENCY

Question 4

This is the most common type of hemophilia

Answer 4

Hemophilia A

Question 5

Hemophilia A is AKA?

Answer 5

Classic hemophilia

Question 6

This is a sex linked disorder characterized by a deficiency in factor VIII:C

Answer 6

Hemophilia A

Question 7

Hemophilia A is characterized by a deficiency in ?

Answer 7

Factor VIII:C

Question 8

What is the therapy done in Hemophilia A?

Answer 8

Commercial VIII concentrate
DDAVP

Question 9

This will increase the factor VII inside the body and will allow the release of stored vWF?

Answer 9

Desmopressin

Question 10

Desmopressin will increase the________ inside the body and will allow the release of stored ______?

Answer 10

Factor VII
vWF

Question 12

This can exhibit mild hemophilia A

Answer 12

Normandy vWF

Question 13

Hemophilia B is AKA?

Answer 13

Christmas disease
Royal disease

Question 14

The hemophilia B is AKA royal disease because?

Answer 14

It is because of queen victoria

Question 15

This is a sex linked disorder characterized by a deficiency of factor IX?

Answer 15

Hemophilia B

Question 16

Hemophilia B is a sex linked disorder characterized by a deficiency of what factor?

Answer 16

Factor IX

Question 17

Who is the first person to have hemophilia B?

Answer 17

Stephen christmas

Question 18

This is the second most common hemophilia, exhibiting clinical signs and symptoms similar to A?

Answer 18

Hemophilia B

Question 19

What is the therapy done in Hemophilia B?

Answer 19

Factor IX concentrate

Question 20

What is the result of the coagulation test in hemophilia A and B?

Answer 20

Both PT and APTT are prolonged

Question 21

What is the confirmatory test used in hemophilia B?

Answer 21

Factor IX assay

Question 22

What is the other name of hemophilia C?

Answer 22

Rosenthal syndrome

Question 23

Hemophilia C is AKA?

Answer 23

Silent type of hemophilia

Question 24

This is an autosomal recessive disorder characterized by a deficiency in factor XI?

Answer 24

Hemophilia C

Question 26

Hemophilia C is an autosomal recessive disorder characterized by a deficiency of what factor?

Answer 26

Factor XI

Question 27

Hemophilia C is increased among?

Answer 27

Ashkenazi Jews

Question 28

What type of hemophilia is this: Bleeding is mild unless stressed by trauma or injury?

Answer 28

Hemophilia C

Question 29

What is the therapy done in hemophilia C?

Answer 29

Fresh frozen plasma or whole blood

Question 30

These are autosomal recessive disorders with no associated bleeding tendencies?

Answer 30

Prekallikrein

Question 31

What is the coagulation result of hemophilia C and Prekallikrein?

Answer 31

PT is prolonged

Question 32

What is the rarest deficiency in Prekallikrein?

Answer 32

Factor I deficiency

Question 33

What is the most profound deficiency in prekallikrein?

Answer 33

Factor VII deficiency

Question 34

Factor VII is most profound because of what reasons?

Answer 34

Presence of proteinemia Increase level of immunoglobulins in the blood

Question 35

What is the reason why there is an increase of immunoglobulins in blood?

Answer 35

Increase viscosity of the blood Lead to kidney damage