DISORDERS OF FIBRINOLYSIS AND THROMBOTIC DISORDERS Flashcards
Enumerate the disorders of fibrinolysis
Primary fibrinolysis
Secondary fibrinolysis
This is an insoluble protein
Fibrinogen
This is due to the release of excessive activators of plasminogen, resulting in the conversion of plasminogen to plasmin in the absence of fibrin.
Primary fibrinolysis
True or false: a clot will be formed under primary fibrinolysis
False: none
What treatment is done under PF?
Introduction of anti-fibrinolytic drugs
Antiplasmin
The clot dissolution results in the increase of FSP/FDP that interfere with coagulation and platelet function
Secondary fibrinolysis
Primary fibrinolysis : fibrinogen lysis
2nd fibrinolysis:
Fibrin lysis
Under SF, there is a clot but it is?
Abnormal
Enumerate the thrombotic disorder
Arterial thrombosis
Venous thrombosis
The arterial thrombosis is AKA?
White clot
This is composed of platelets with a small amount of fibrin, red cells and white cells?
Arterial thrombosis
Arterial thrombosis is composed of platelets with a _____________, _________, __________?
small amount of fibrin, red cells and white cells
Venousl thrombosis is composed of platelets with a _____________, _________, __________?
Large amount of fibrin, red cells and few platelets
Patients that have these diseases can manifest arterial thrombosis?
Stroke and diabetic patient
This is composed of platelets with a large amount of fibrin, red cells and few platelets?
Venous thrombosis
Venous thrombosis is associated with?
Slow blood flow
Activation of coagulation
Impairment of fibrinolytic system
Deficiency of physiological inhibitors