Inheritance, Variation And Evlolution 🏔 Flashcards
What are the two types of cell division?
Mitosis- asexual
meiosis- sexual
How does meiosis occur + what does it require?
The sperm fuses with the egg (fertilisation)
Forming a zygote
Within the zygote, the genetic material duplicates
They line up and get pulled apart by cell fibres
causing the nucleus to divide in two
A second diffusion occurs
This leads to 4 genetically different sex cells being formed
Requires a mum and dad
What does mitosis require + produce?
1 parent
Only 1 cell division
No gamete fusion (asexual)
Offspring are clones (identical daughter cells)
What happens as soon as the embryo reaches a certain size in sexual reproduction?
Cells start to specialise
Advantages of sexual reproduction?
Artificial selection eg selective breeding
Variation of offspring - higher survival rate due to being able to adapt to changes in environment
Advantages of asexual reproduction ?
Lots of identical offspring is conditions a favourable
No mate
Faster
What makes a chromosome ?
Coil of DNA makes of genes
What does the genome sequencing help us understand?
Inherited disorders/how it can be treated
Gene identification
Human migratory history
What is DNA
a polymer (covalently bonded)made up of a double helix
What are the genes code made up of ?
Amino acids for specific proteins
What is the genome sequence made up of?
Chromosome
DNA
gene
What is a nucleotide made up of? What does T pair up with and what does G
Phosphate sugar and base
T-A
G-C
What are protiens ?
Polymers of amino acids
How many protiens are in humans ?
23
What does the order of the amino acids (sequence of bases) in the protein determine ?
The shape and function of the protein
What is the first stage of protein synthesis?
1.transcription occurs in nucleus - base sequence is copies into a complementary template called MRNA (single stranded molecule)
What is the second stage of protein synthesis?
MRNA passes through the nucleus into the cytoplasm TRANSLATION
MRNA molecule attaches to a ribosome
Amino acids attaches to ribosome on carrier molecules TRNA
Ribosome connects TRNA in right order
Once complete, the protein chain folds in its unique shape enabling it to do its job .
How many base codes are there?
3 (triplets)
What happened if a code
uncomplementary Changes in a protein chain? What does it lead to the active state becoming?
Mutation occurs resulting in a change in protein shape leading to an active site being no longer complementary to substate
What happens if a protein mutates at the wrong time ?
Uncontrolled mitosis leading to cancer
What is non-coding DNA?
DNA that does not encode protein sequences
What is cystic fibrosis?
What disorder is it?
An inherited disorder of a large build up of mucus in the lungs
Disorder of cell membranes
Advantages of embryo screening?
Financial saving of medical bills
Prevent suffering from genetic orders
Able to view future implications
What type of screening is embryo screening?
Genome
Disadvantages of embryo screening
Course cause discrimination
Expensive
Injustice (selective parents)
Unused embryos destroyed- unethical- killing human life
What are the men / woman genes
XY-men
Women-XX
How does selective breading take place
Pick 2 to be parents
Bred them
Pick offspring
Bread them
Carry on until appearance desires are met
What do selective breeders have to make sure? Why?
No unhealthy interbreeds
If so, could cause inheritary diseases
What is Darwin’s approach on natural selection?
- Genetic variation
(different genes are within the population) - Survival of the fittest ( alleles are favourable )
- Successful breading (favourable genes gets passed down to offspring)
- Best characterises survive
Criticisms of Darwin?
- Genes not discover
- Evidence was inconclusive
- Went against Christianity that god created the world
What was Lamark’s INCORRECT idea of evolution ? Why was he wrong?
Baby Giraffes gained their long neck characteristics but stretching it to eatleaves form trees, rather than it being a genetic feature this then gets passed on to offspring
THIS IS WRONG because changes of An animals lifetime do not get passes on to future generations.
What’s are the monomers that build up DNA called?
Nucleotides
How can a mutation in a gene result in a protein not carrying out its role correctly?
Mutation may carry a code for a different amino acid
Which could alter the structure of the Protein
Making it the wrong shape to transport water
What are fossils ?
Remains of organisms from millions of years ago found in rocks
When are the 3 ways that fossils can be formed ? + Examples?
- When parts of an organism have not decayed e.g temp too cold not enough oxygen or water
- When part of an organism has decayed if the parts of the organism is replaced by minerals
- Preserves traces of organisms eg. Footprint
What were some problems of older organisms forming into skeletons ?
What does it lead to scientist thinking?
Where soft bodies - no skeletons
So rarely formed fossils
If it did , they were crushed by the earth’s crust
This makes scientist unable to know how life on earth started
What are the 4 ways species can become extinct?
- Catastrophic event eg. Astroid
2.environmental changes eg. Change of weather patterns
- New disease or new predator
- New successful species evolve and competes with it for food or water
How many minutes can bacteria reproduce?
Why can bacteria evolve rapidly?
Every 30 minutes
They can evolve rapidly as the reproduce at a fast rate.
What antibiotic was first created ?
Penicillin
What is one common antibiotic strain of resistant bacteria?
MRSA
How do antibiotic resistant bacteria form ?
Why does the resistant strain spread?
- Genetic variation takes place , some bacterias have favourable genes due to mutations
- All bacteriums are killed except for the resistant one causing it to reproduce by mitosis with no competition
- This causes the resistant bacteria population to rise
- The resistant stain now spreads as people are not immune to it and no effective treatment
How can we reduce the amount of antibiotic resistant bacteria? (3 ways )
- Doctors show not prescribe unnecessary antibiotic inappropriately as they have no effect
- Patients need to complete the whole course of antibiotics making sure all bacterias have been killed and none have survived to mutate and form resistant strains
- Reduce the use of antibiotics in farming
What are the negative of scientists developing new antibiotics?
Takes too long + expensive
Unlikely to keep up as new bacterias emerge all the time
Apart from genes , what are the two main sources of evidence from evolution
Fossils
antibiotic resistant bacteria
What is a gene?
A section is DNA on a chromosome